Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 8/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29402990 | 1.00 | ATM (0.50) | ATMDPP4DPP8DPP9ACE | |
| SCHEMBL4432634 | 1.00 | ATM (0.50) | ATMDPP4DPP8DPP9ACE | |
| SCHEMBL34461081 | 0.89 | ATM (0.51) | ATMDPP4DPP8DPP9ACE | |
| SCHEMBL4432639 | 0.89 | ATM (0.51) | ATMDPP4DPP8DPP9ACE | |
| SCHEMBL4432650 | 0.89 | ATM (0.51) | ATMDPP4DPP8DPP9ACE | |
| SCHEMBL4430344 | 0.87 | DPP4 (0.53) | ATMDPP4DPP8DPP9ACE | |
| SCHEMBL4430341 | 0.87 | DPP4 (0.53) | ATMDPP4DPP8DPP9ACE | |
| SCHEMBL30069049 | 0.85 | ACE (0.42) | ATMDPP4ACE | |
| SCHEMBL4435209 | 0.84 | ATM (0.53) | ATMDPP4DPP8DPP9ACE | |
| SCHEMBL29570282 | 0.84 | ATM (0.53) | ATMDPP4DPP8DPP9ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250369050-A1 | METHODS AND COMPOSITIONS RELATED TO ASSESSMENT AND TREATMENT OF KIDNEY DISEASE | UNIV TEXAS (US) | 2025-12-04 | — | — | US | disclosed |
| EP-4473316-A2 | METHODS AND COMPOSITIONS RELATED TO ASSESSMENT AND TREATMENT OF KIDNEY DISEASE | Board of Regents, The University of Texas System (US) | 2024-12-11 | — | — | EP | disclosed |
| WO-2023150736-A2 | METHODS AND COMPOSITIONS RELATED TO ASSESSMENT AND TREATMENT OF KIDNEY DISEASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-08-10 | — | — | WO | disclosed |