SCHEMBL4430341

SCHEMBL4430341

NC(=O)CCC(N)C(=O)N1CC(O)CC1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 7/20 0.53
DPP8 Q6V1X1 7/20 0.53
DPP9 Q86TI2 7/20 0.53
ATM Q13315 1/20 0.49
ALOX15 P16050 1/20 0.43
BLM P54132 1/20 0.43
PMP22 Q01453 1/20 0.43
KMT2A Q03164 1/20 0.43
ACE P12821 3/20 0.38
FAP Q12884 1/20 0.38
DPP7 Q9UHL4 1/20 0.38
PRSS1 P07477 2/20 0.37
TMPRSS15 P98073 2/20 0.37
ARG1 P05089 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4430344 1.00 DPP4 (0.53) DPP4DPP8DPP9ATMALOX15
SCHEMBL28821947 0.90 DPP4 (0.66) DPP4DPP8DPP9ATMACE
SCHEMBL31540102 0.90 DPP4 (0.66) DPP4DPP8DPP9ATMACE
SCHEMBL29396034 0.90 DPP4 (0.66) DPP4DPP8DPP9ATMACE
SCHEMBL25336372 0.87 ATM (0.50) DPP4DPP8DPP9ATMACE
SCHEMBL4432634 0.87 ATM (0.50) DPP4DPP8DPP9ATMACE
SCHEMBL29402990 0.87 ATM (0.50) DPP4DPP8DPP9ATMACE
SCHEMBL29689276 0.85 DPP4 (0.44) DPP4DPP8DPP9ACEFAP
SCHEMBL5788741 0.84 ALOX15 (0.42) DPP4DPP8DPP9ALOX15BLM
SCHEMBL5788998 0.84 ALOX15 (0.42) DPP4DPP8DPP9ALOX15BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240262882-A1 NOVEL RECEPTORS FOR LIGAND-DEPENDENT TRANSCRIPTIONAL REGULATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-08-08 US disclosed
US-11897932-B2 Receptors for ligand-dependent transcriptional regulation THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-02-13 US disclosed
EP-4034553-A1 NOVEL RECEPTORS FOR LIGAND-DEPENDENT TRANSCRIPTIONAL REGULATION Regents of the University of California (US) 2022-08-03 EP disclosed
CN-114729025-A Novel receptors for ligand-dependent transcriptional regulation 加利福尼亚大学董事会 2022-07-08 CN disclosed
EP-2117536-A2 COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS Beiersdorf AG (DE) 2009-11-18 EP disclosed
WO-2008101693-A2 COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS BEIERSDORF AG (DE) 2008-08-28 WO disclosed