Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222349 | 0.93 | IDO1 (0.50) | IDO1MEN1KMT2ALMNAHTT | |
| SCHEMBL25336501 | 0.83 | IDO1 (0.42) | IDO1MEN1KMT2ALMNAHTT | |
| SCHEMBL360527 | 0.80 | — | — | |
| SCHEMBL4444390 | 0.75 | HTT (0.52) | IDO1MEN1KMT2ALMNAHTT | |
| SCHEMBL31393144 | 0.75 | IDO1 (0.50) | IDO1MEN1KMT2ALMNAHTT | |
| SCHEMBL987475 | 0.74 | IDO1 (0.53) | IDO1MEN1KMT2ALMNAHTT | |
| SCHEMBL986221 | 0.73 | TDP1 (0.52) | IDO1MEN1KMT2ALMNAHTT | |
| SCHEMBL30122384 | 0.73 | TDP1 (0.52) | IDO1MEN1KMT2ALMNAHTT | |
| SCHEMBL936212 | 0.72 | HTT (0.57) | IDO1MEN1KMT2ALMNAHTT | |
| SCHEMBL1162908 | 0.72 | ALDH1A1 (0.57) | IDO1MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146989-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |