SCHEMBL25337355

SCHEMBL25337355

CC(C)CC(C)Nc1ccc2c(c1)Sc1ccccc1N2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 12/20 0.47
GAA P10253 6/20 0.47
MAPT P10636 6/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
MAPK1 P28482 3/20 0.47
TDP1 Q9NUW8 3/20 0.47
LMNA P02545 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ALOX15 P16050 4/20 0.47
ALDH1A1 P00352 3/20 0.47
CYP3A4 P08684 2/20 0.47
ALOX12 P18054 2/20 0.47
TSHR P16473 2/20 0.47
HSD17B10 Q99714 2/20 0.47
HIF1A Q16665 1/20 0.47
SNCA P37840 3/20 0.46
BCHE P06276 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25337919 0.84 NOX1 (0.53) NOX1GAAMAPTMEN1KMT2A
SCHEMBL29441280 0.84 NOX1 (0.53) NOX1GAAMAPTMEN1KMT2A
SCHEMBL20398351 0.80 TDP1 (0.53) NOX1GAAMAPTMEN1KMT2A
Hydrochloric Acid SCHEMBL20398345 0.79 TDP1 (0.52) NOX1GAAMAPTMEN1KMT2A
SCHEMBL20488743 0.76 NOX1 (0.59) NOX1GAAMAPTMEN1KMT2A
SCHEMBL20398354 0.76 SNCA (0.46) NOX1GAAMAPTMEN1KMT2A
SCHEMBL25204884 0.76 ALDH1A1 (0.47) GAAMAPTMEN1KMT2AMAPK1
SCHEMBL30416967 0.76 ALDH1A1 (0.47) GAAMAPTMEN1KMT2AMAPK1
SCHEMBL25611975 0.76 ALDH1A1 (0.47) MAPTMAPK1TDP1LMNAL3MBTL1
SCHEMBL26187586 0.75 CDK5 (0.51) MEN1KMT2AMAPK1ALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12479810-B2 Phenothiazine compound, its preparation and use in rubber blends and vehicle tires, as ageing protectant, antioxidant, antiozonant and colorant CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2025-11-25 US disclosed
CN-116323786-B Phenothiazine compounds, their preparation and their use as age protectors, antioxidants, antiozonants and colorants in rubber blends and vehicle tires 大陆轮胎德国有限公司 2025-05-23 CN disclosed
EP-4222146-B1 PHENOTHIAZINE COMPOUND, ITS PREPARATION AND USE IN RUBBER BLENDS AND VEHICLE TIRES, AS AGEING PROTECTANT, ANTIOXIDANT, ANTIOZONANT AND COLORANT CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2024-07-10 EP disclosed
EP-4222146-B1 PHENOTHIAZINE COMPOUND, ITS PREPARATION AND USE IN RUBBER BLENDS AND VEHICLE TIRES, AS AGEING PROTECTANT, ANTIOXIDANT, ANTIOZONANT AND COLORANT CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2024-07-10 EP disclosed
CN-117466747-A Preparation method of anti-aging agent 汤阴永新化学有限责任公司 2024-01-30 CN disclosed
US-20240018112-A1 PHENOTHIAZINE COMPOUND, ITS PREPARATION AND USE IN RUBBER BLENDS AND VEHICLE TIRES, AS AGEING PROTECTANT, ANTIOXIDANT, ANTIOZONANT AND COLORANT CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2024-01-18 US disclosed
US-20240018112-A1 PHENOTHIAZINE COMPOUND, ITS PREPARATION AND USE IN RUBBER BLENDS AND VEHICLE TIRES, AS AGEING PROTECTANT, ANTIOXIDANT, ANTIOZONANT AND COLORANT CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2024-01-18 US disclosed
EP-4222146-A1 PHENOTHIAZINE COMPOUND, ITS PREPARATION AND USE IN RUBBER BLENDS AND VEHICLE TIRES, AS AGEING PROTECTANT, ANTIOXIDANT, ANTIOZONANT AND COLORANT Continental Reifen Deutschland GmbH (DE) 2023-08-09 EP disclosed
CN-116323786-A Phenothiazine compounds, their preparation and their use as age protectors, antioxidants, antiozonants and colorants in rubber blends and vehicle tires 大陆轮胎德国有限公司 2023-06-23 CN disclosed
WO-2022069001-A1 PHENOTHIAZINE COMPOUND, ITS PREPARATION AND USE IN RUBBER BLENDS AND VEHICLE TIRES, AS AGEING PROTECTANT, ANTIOXIDANT, ANTIOZONANT AND COLORANT CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2022-04-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479810-B2 Phenothiazine compound, its preparation and use in rubber blends and vehicle tires, as ageing protectant, antioxidant, antiozonant and colorant POT1, HTT, TERB1 NOX1 794/4885GAA 1603/4885MAPT 24/4885
US-20240018112-A1 PHENOTHIAZINE COMPOUND, ITS PREPARATION AND USE IN RUBBER BLENDS AND VEHICLE TIRES, AS AGEING PROTECTANT, ANTIOXIDANT, ANTIOZONANT AND COLORANT POT1, HTT, TERB1 NOX1 794/4885GAA 1603/4885MAPT 24/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.