SCHEMBL25337989

SCHEMBL25337989

Cc1oc(-c2ccc(N)cc2)nc1C1CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 1/20 0.44
▸ NPC1 O15118 14/20 0.43
▸ RAB9A P51151 14/20 0.43
▸ ALDH1A1 P00352 7/20 0.41
▸ KDM4E B2RXH2 7/20 0.41
▸ MAPT P10636 6/20 0.41
▸ SMN1; SMN2 Q16637 6/20 0.41
▸ MEN1 O00255 6/20 0.41
▸ KMT2A Q03164 6/20 0.41
▸ HPGD P15428 5/20 0.41
▸ GLA P06280 2/20 0.41
▸ GFER P55789 2/20 0.41
▸ RXFP1 Q9HBX9 2/20 0.41
▸ ATM Q13315 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ HSD17B10 Q99714 6/20 0.41
▸ TP53 P04637 5/20 0.41
▸ NFKB1 P19838 3/20 0.41
▸ NFKB2 Q00653 3/20 0.41
▸ RELA Q04206 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25956015 0.79 FLT3 (0.32) NPC1RAB9ASMN1; SMN2TP53L3MBTL1
SCHEMBL25338984 0.78 MAPT (0.51) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
Hydrochloric Acid SCHEMBL30511234 0.78 FLT3 (0.32) NPC1RAB9ASMN1; SMN2TP53L3MBTL1
SCHEMBL24125061 0.75 RAB9A (0.52) ACHENPC1RAB9AALDH1A1KDM4E
SCHEMBL26050670 0.72 CCNA2 (0.36) ALDH1A1KDM4E
SCHEMBL10238101 0.72 TARBP2 (0.41) NPC1RAB9AALDH1A1KDM4EMAPT
SCHEMBL4260812 0.69 RAB9A (0.56) ACHENPC1RAB9AALDH1A1KDM4E
SCHEMBL26195227 0.69 NPC1 (0.48) NPC1RAB9AALDH1A1KDM4EMAPT
SCHEMBL25340904 0.68 CA1 (0.65) NPC1RAB9AALDH1A1KDM4EMAPT
SCHEMBL12794378 0.68 PIK3CB (0.49) ACHENPC1RAB9AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250136559-A1 SMO MODULATOR COMPOUNDS Omass Therapeutics Limited (GB) 2025-05-01 — — US disclosed
EP-4472959-A1 SMO MODULATOR COMPOUNDS Omass Therapeutics Limited (GB) 2024-12-11 — — EP disclosed
WO-2023148481-A1 SMO MODULATOR COMPOUNDS Omass Therapeutics Limited (GB) 2023-08-10 — — WO disclosed
WO-2023148481-A1 SMO MODULATOR COMPOUNDS Omass Therapeutics Limited (GB) 2023-08-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136559-A1 SMO MODULATOR COMPOUNDS SMO, SHH, GLI1 ACHE 1927/4885NPC1 876/4885RAB9A 863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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