Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27805357 | 0.76 | PTGS2 (0.58) | PTGS2PTGS1ADORA2AADORA1NPC1 | |
| SCHEMBL27810856 | 0.75 | HTR2A (0.37) | PTGS2NPC1MAPTRAB9A | |
| SCHEMBL6725713 | 0.74 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL12326172 | 0.74 | PTGS2 (0.53) | PTGS2PTGS1ADORA2AADORA1NPC1 | |
| SCHEMBL6368263 | 0.74 | PTGS2 (0.56) | PTGS2PTGS1HSD17B1HSD17B2NPC1 | |
| Sulfamide SCHEMBL4638382 | 0.73 | PTGS2 (0.77) | PTGS2PTGS1ADORA2AADORA1 | |
| SCHEMBL214380 | 0.73 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL13906296 | 0.72 | PTGS2 (0.50) | PTGS2PTGS1NPC1RAB9A | |
| SCHEMBL1098582 | 0.71 | NPC1 (0.45) | PTGS2PTGS1NPC1MAPTRAB9A | |
| SCHEMBL17694924 | 0.71 | ERN1 (0.55) | PTGS2PTGS1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4221703-A1 | HSD17B13 INHIBITORS AND USES THEREOF | FL2022-001, Inc. (US) | 2023-08-09 | — | — | EP | disclosed |