Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL25338596

Cc1ccc(O)c(C(=O)O)c1.N

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 1/20 0.96
MCL1 Q07820 5/20 0.69
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
PTGS2 P35354 2/20 0.59
CA12 O43570 1/20 0.59
ALOX5 P09917 1/20 0.59
CA7 P43166 1/20 0.59
CA9 Q16790 1/20 0.59
CA14 Q9ULX7 1/20 0.59
PTPN1 P18031 2/20 0.57
PTPN2 P17706 1/20 0.57
PTPN6 P29350 1/20 0.57
ALDH1A1 P00352 3/20 0.55
MEN1 O00255 2/20 0.55
KDR P35968 2/20 0.55
KMT2A Q03164 2/20 0.55
KDM4E B2RXH2 1/20 0.55
TNF P01375 1/20 0.55
CYP3A4 P08684 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127149 0.98 CSNK2A1 (1.00) CSNK2A1MCL1CA1CA2PTGS2
SCHEMBL29740060 0.98 CSNK2A1 (1.00) CSNK2A1MCL1CA1CA2PTGS2
Bromide SCHEMBL10876570 0.96 CSNK2A1 (0.96) CSNK2A1MCL1CA1CA2PTGS2
Hydrochloric Acid SCHEMBL10875048 0.96 CSNK2A1 (0.96) CSNK2A1MCL1CA1CA2PTGS2
SCHEMBL18741295 0.96 CSNK2A1 (0.96) CSNK2A1MCL1CA1CA2PTGS2
SCHEMBL18741297 0.96 CSNK2A1 (0.96) CSNK2A1MCL1CA1CA2PTGS2
Ethane SCHEMBL27837259 0.96 CSNK2A1 (0.96) CSNK2A1MCL1CA1CA2PTGS2
Formaldehyde SCHEMBL11413714 0.94 CSNK2A1 (0.92) CSNK2A1MCL1CA1CA2PTGS2
SCHEMBL4292219 0.90 CSNK2A1 (0.85) CSNK2A1MCL1CA1CA2PTGS2
SCHEMBL9769750 0.84 CSNK2A1 (0.73) CSNK2A1MCL1CA1CA2PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230251277-A1 METHOD FOR DETERMINING THE LEVEL OF VITAMIN D AND METABOLITES THEREOF ROCHE DIAGNOSTICS OPERATIONS, INC. 2023-08-10 US disclosed
EP-4222502-A1 A METHOD FOR DETERMINING THE LEVEL OF VITAMIN D AND METABOLITES THEREOF F. Hoffmann-La Roche AG (CH) 2023-08-09 EP disclosed
CN-116209901-A Method for determining the amount of vitamin D and its metabolites 豪夫迈·罗氏有限公司 2023-06-02 CN disclosed
WO-2022069392-A1 A METHOD FOR DETERMINING THE LEVEL OF VITAMIN D AND METABOLITES THEREOF F. HOFFMANN-LA ROCHE AG (CH) 2022-04-07 WO disclosed