SCHEMBL4292219

SCHEMBL4292219

C1=CC1.Cc1ccc(O)c(C(=O)O)c1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 1/20 0.85
MCL1 Q07820 5/20 0.62
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
PTGS2 P35354 2/20 0.53
CA12 O43570 1/20 0.53
ALOX5 P09917 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
PTPN1 P18031 2/20 0.52
PTPN2 P17706 1/20 0.52
PTPN6 P29350 1/20 0.52
ALDH1A1 P00352 3/20 0.50
MEN1 O00255 2/20 0.50
KDR P35968 2/20 0.50
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 1/20 0.50
TNF P01375 1/20 0.50
CYP3A4 P08684 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127149 0.92 CSNK2A1 (1.00) CSNK2A1MCL1CA1CA2PTGS2
SCHEMBL29740060 0.92 CSNK2A1 (1.00) CSNK2A1MCL1CA1CA2PTGS2
Ammonia Solution, Strong SCHEMBL25338596 0.90 CSNK2A1 (0.96) CSNK2A1MCL1CA1CA2PTGS2
Hydrochloric Acid SCHEMBL10875048 0.90 CSNK2A1 (0.96) CSNK2A1MCL1CA1CA2PTGS2
Ethane SCHEMBL27837259 0.90 CSNK2A1 (0.96) CSNK2A1MCL1CA1CA2PTGS2
SCHEMBL18741295 0.90 CSNK2A1 (0.96) CSNK2A1MCL1CA1CA2PTGS2
Bromide SCHEMBL10876570 0.90 CSNK2A1 (0.96) CSNK2A1MCL1CA1CA2PTGS2
SCHEMBL18741297 0.90 CSNK2A1 (0.96) CSNK2A1MCL1CA1CA2PTGS2
Formaldehyde SCHEMBL11413714 0.88 CSNK2A1 (0.92) CSNK2A1MCL1CA1CA2PTGS2
SCHEMBL9769750 0.82 CSNK2A1 (0.73) CSNK2A1MCL1CA1CA2PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8071518-B2 Low ash engine oil composition NIPPON OIL CORPORATION (JP) 2011-12-06 US disclosed
US-7629302-B2 Lubricating oil additive and lubricating oil composition NIPPON OIL CORPORATION (JP) 2009-12-08 US disclosed
US-20090075852-A1 Low Ash Engine Oil Composition NIPPON OIL CORPORATION (JP) 2009-03-19 US disclosed
EP-1997871-A1 LOW-ASH ENGINE OIL COMPOSITION Nippon Oil Corporation (JP) 2008-12-03 EP disclosed
CN-100347277-C Lubricating oil additive and lubricating oil composition NIPPON OIL CORP (JP) 2007-11-07 CN disclosed
CN-100344740-C Lubricating oil composition NIPPON OIL CORP (JP) 2007-10-24 CN disclosed
US-20060063686-A1 Lubricating oil additive and lubricating oil composition NIPPON OIL CORPORATION (JP) 2006-03-23 US disclosed
CN-1714140-A Lubricating oil additive and lubricating oil composition NIPPON OIL CORP (JP) 2005-12-28 CN disclosed
EP-1580257-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2005-09-28 EP disclosed
CN-1675342-A Lubricating oil composition NIPPON OIL CORP (JP) 2005-09-28 CN disclosed