Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30544058 | 1.00 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL25339701 | 0.80 | TEAD1 (0.40) | MAPTMAT2A | |
| SCHEMBL30544052 | 0.80 | TEAD1 (0.40) | MAPTMAT2A | |
| SCHEMBL25952101 | 0.79 | BRD4 (0.39) | GPR139 | |
| SCHEMBL25429043 | 0.72 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL25377567 | 0.69 | DYRK1A (0.50) | SLC6A2SLC6A4SLC6A3ALDH1A1HTR1A | |
| SCHEMBL25978187 | 0.69 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL25973620 | 0.68 | KCNQ3 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25973625 | 0.67 | DHODH (0.46) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL25973835 | 0.67 | SLC6A4 (0.41) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |