Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25429629 | 0.80 | TRPV1 (0.46) | TRPV1MAPTSCN5ASCN9AMCHR1 | |
| SCHEMBL25952233 | 0.79 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL25429357 | 0.79 | TP53 (0.42) | TRPV1MAPTSCN5ASCN9AMCHR1 | |
| SCHEMBL25429595 | 0.77 | TRPV1 (0.37) | TRPV1SCN5ASCN9AMCHR1KIF11 | |
| SCHEMBL25430647 | 0.76 | HSD17B10 (0.55) | SLC6A2SLC6A4SLC6A3TRPV1KDM4E | |
| Hydrochloric Acid SCHEMBL10631649 | 0.73 | KIF11 (0.47) | KDM4EMAPTSCN5ASCN9AKIF11 | |
| SCHEMBL30544058 | 0.72 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL25339003 | 0.72 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL25978187 | 0.71 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL25430599 | 0.69 | PTGS2 (0.50) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |