Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.44 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28708634 | 1.00 | GPR119 (0.49) | GPR119JAK2JAK1DPP4USP30 | |
| Ammonia Solution, Strong SCHEMBL29508647 | 1.00 | GPR119 (0.49) | GPR119JAK2JAK1DPP4USP30 | |
| Ammonia Solution, Strong SCHEMBL29508702 | 1.00 | GPR119 (0.49) | GPR119JAK2JAK1DPP4USP30 | |
| Ammonia Solution, Strong SCHEMBL25436483 | 1.00 | GPR119 (0.49) | GPR119JAK2JAK1DPP4USP30 | |
| Ammonia Solution, Strong SCHEMBL28702321 | 1.00 | GPR119 (0.49) | GPR119JAK2JAK1DPP4USP30 | |
| Ammonia Solution, Strong SCHEMBL25339067 | 1.00 | GPR119 (0.49) | GPR119JAK2JAK1DPP4USP30 | |
| SCHEMBL23751498 | 0.99 | GPR119 (0.50) | GPR119JAK2JAK1DPP4USP30 | |
| SCHEMBL22765131 | 0.99 | GPR119 (0.50) | GPR119JAK2JAK1DPP4USP30 | |
| SCHEMBL22765135 | 0.99 | GPR119 (0.50) | GPR119JAK2JAK1DPP4USP30 | |
| SCHEMBL22750862 | 0.99 | GPR119 (0.50) | GPR119JAK2JAK1DPP4USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146785-A1 | PYRROLIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2023-08-03 | — | — | WO | disclosed |