Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 17/20 | 0.62 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25339743 | 0.87 | TRPV1 (0.62) | TRPV1EGFREPHX2 | |
| SCHEMBL25951982 | 0.86 | TRPV1 (0.53) | TRPV1EPHX2 | |
| SCHEMBL25340961 | 0.79 | TRPV1 (0.45) | TRPV1 | |
| Ngd-8243 SCHEMBL2730820 | 0.77 | TRPV1 (1.00) | TRPV1 | |
| Ngd-8243 SCHEMBL29706343 | 0.77 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL25340324 | 0.77 | TRPV1 (0.54) | TRPV1 | |
| SCHEMBL25974211 | 0.77 | TRPV1 (0.45) | TRPV1CNR1EPHX2 | |
| SCHEMBL4970898 | 0.76 | TRPV1 (0.79) | TRPV1EGFREPHX2 | |
| SCHEMBL30482575 | 0.75 | KCNQ3 (0.47) | TRPV1EPHX2 | |
| SCHEMBL25378382 | 0.75 | KCNQ3 (0.47) | TRPV1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |