Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.47 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.47 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.44 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25378382 | 1.00 | KCNQ3 (0.47) | KCNQ3KCNQ2KCNQ1KCNE1TRPA1 | |
| SCHEMBL25377441 | 0.86 | EPHX2 (0.47) | TRPV1CTSCEPHX2 | |
| SCHEMBL30482543 | 0.86 | EPHX2 (0.47) | TRPV1CTSCEPHX2 | |
| SCHEMBL25376256 | 0.82 | KCNQ3 (0.48) | KCNQ3KCNQ2KCNQ1KCNE1TRPA1 | |
| SCHEMBL30482518 | 0.81 | TRPV1 (0.46) | TRPV1EPHX2 | |
| SCHEMBL25377909 | 0.81 | TRPV1 (0.46) | TRPV1EPHX2 | |
| SCHEMBL30482578 | 0.81 | TRPV1 (0.42) | TRPV1CTSCEPHX2 | |
| SCHEMBL25375839 | 0.81 | TRPV1 (0.44) | TRPV1EPHX2 | |
| SCHEMBL25374304 | 0.81 | TRPV1 (0.42) | TRPV1CTSCEPHX2 | |
| SCHEMBL25340913 | 0.81 | KIF11 (0.51) | TRPV1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146512-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |