Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 3/20 | 0.70 |
| ▸ | OSBP2 | Q969R2 | 3/20 | 0.70 |
| ▸ | NPC1L1 | Q9UHC9 | 6/20 | 0.57 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.57 |
| ▸ | CRYAB | P02511 | 1/20 | 0.57 |
| ▸ | HMGCR | P04035 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGAV | P06756 | 1/20 | 0.57 |
| ▸ | RORC | P51449 | 1/20 | 0.57 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | GPR183 | P32249 | 5/20 | 0.52 |
| ▸ | VDR | P11473 | 3/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25337771 | 1.00 | OSBP (0.70) | OSBPOSBP2NPC1L1NR1H3CRYAB | |
| SCHEMBL25336826 | 0.89 | OSBP (0.67) | OSBPOSBP2NPC1L1NR1H3CRYAB | |
| SCHEMBL7117472 | 0.87 | NPC1L1 (0.66) | OSBPOSBP2NPC1L1RORCPTPN1 | |
| SCHEMBL16226011 | 0.87 | NPC1L1 (0.66) | OSBPOSBP2NPC1L1RORCPTPN1 | |
| SCHEMBL7117470 | 0.87 | NPC1L1 (0.66) | OSBPOSBP2NPC1L1RORCPTPN1 | |
| SCHEMBL16225645 | 0.87 | NPC1L1 (0.66) | OSBPOSBP2NPC1L1RORCPTPN1 | |
| SCHEMBL16226436 | 0.87 | NPC1L1 (0.66) | OSBPOSBP2NPC1L1RORCPTPN1 | |
| SCHEMBL16225777 | 0.87 | NPC1L1 (0.66) | OSBPOSBP2NPC1L1RORCPTPN1 | |
| SCHEMBL25336190 | 0.87 | OSBP (0.64) | OSBPOSBP2NPC1L1NR1H3CRYAB | |
| SCHEMBL25337599 | 0.87 | OSBP (0.59) | OSBPOSBP2NPC1L1NR1H3CRYAB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143399-A1 | STEROID COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 珂阑(上海)医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |