SCHEMBL253401

SCHEMBL253401

CCCCCCCCN1CCCN2CCCN=C12

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
CYP2D6 P10635 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP1A2 P05177 2/20 0.40
TSHR P16473 1/20 0.39
HTT P42858 1/20 0.39
CYP2C19 P33261 2/20 0.35
CYP3A4 P08684 1/20 0.35
GBA1 P04062 1/20 0.35
ALOX5 P09917 2/20 0.33
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL250783 1.00 ALDH1A1 (0.47) ALDH1A1CYP2D6MEN1KMT2ACYP1A2
SCHEMBL31066883 1.00 ALDH1A1 (0.47) ALDH1A1CYP2D6MEN1KMT2ACYP1A2
SCHEMBL31066868 1.00 ALDH1A1 (0.47) ALDH1A1CYP2D6MEN1KMT2ACYP1A2
SCHEMBL9131907 1.00 ALDH1A1 (0.47) ALDH1A1CYP2D6MEN1KMT2ACYP1A2
SCHEMBL17217520 1.00 ALDH1A1 (0.47) ALDH1A1CYP2D6MEN1KMT2ACYP1A2
SCHEMBL31066870 1.00 ALDH1A1 (0.47) ALDH1A1CYP2D6MEN1KMT2ACYP1A2
SCHEMBL8368647 0.98 ALDH1A1 (0.45) ALDH1A1CYP2D6MEN1KMT2ACYP1A2
SCHEMBL252415 0.93 CYP2D6 (0.44) ALDH1A1CYP2D6MEN1KMT2ACYP1A2
SCHEMBL22106056 0.92 ALDH1A1 (0.36) ALDH1A1CYP2D6CYP1A2TSHRHTT
SCHEMBL22106055 0.92 ALDH1A1 (0.36) ALDH1A1CYP2D6CYP1A2TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10640641-B2 Curable coating compositions of silane functional polymers KING INDUSTRIES (US) 2020-05-05 US claimed
US-20200062953-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES 2020-02-27 US claimed
WO-2019157357-A1 PROCESSES FOR PREPARING CALIXARENES SI GROUP, INC. (US) 2019-08-15 WO claimed
US-20190248721-A1 PROCESSES FOR PREPARING CALIXARENES SI GROUP, INC. 2019-08-15 US claimed
US-10336863-B2 Curable composition having a special catalyst/softner system HENKEL AG & CO. KGAA (DE) 2019-07-02 US claimed
US-20180237635-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES 2018-08-23 US claimed
US-9976028-B2 Curable coating compositions of silane functional polymers KING INDUSTRIES (US) 2018-05-22 US claimed
US-9944593-B2 Process for the synthesis of fluoralkyl sulfonate salts SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2018-04-17 US claimed
EP-1930376-B2 CURABLE COMPOSITION KANEKA CORP (JP) 2016-09-07 EP claimed
WO-2016137881-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES (US) 2016-09-01 WO claimed
US-20160244606-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES 2016-08-25 US claimed
WO-2012036392-A3 HUMAN ANTI-EPIDERMAL GROWTH FACTOR RECEPTOR FAB ANTIBODY AND A PHARMACEUTICAL COMPOSITION FOR TREATING TUMOURS COMPRISING THE SAME 주식회사 아이지세라피 (KR) 2012-05-10 WO claimed
EP-1930376-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2011-12-07 EP claimed
US-8013080-B2 Curable composition KANEKA CORPORATION (JP) 2011-09-06 US claimed
EP-4692247-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2026-02-11 EP disclosed
EP-4692148-A1 CURABLE COMPOSITION AND CURED PRODUCT OF SAME DIC Corporation (JP) 2026-02-11 EP disclosed
US-20260022211-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2026-01-22 US disclosed
EP-1992665-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2008-11-19 EP disclosed
EP-1990370-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2008-11-12 EP disclosed
EP-1930376-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2008-06-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190248721-A1 PROCESSES FOR PREPARING CALIXARENES CALU, CALD1, CALR ALDH1A1 254/4885CYP2D6 1274/4885MEN1 4829/4885
US-20260022211-A1 CURABLE COMPOSITION H1-4, H1-0, H1-2 ALDH1A1 2939/4885CYP2D6 3557/4885MEN1 345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.