Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.60 |
| ▸ | BRD4 | O60885 | 4/20 | 0.57 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.57 |
| ▸ | BRD2 | P25440 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23613810 | 0.94 | SMN1; SMN2 (0.69) | L3MBTL1SMN1; SMN2TP53CASP1GLA | |
| SCHEMBL17393986 | 0.93 | L3MBTL1 (0.64) | L3MBTL1SMN1; SMN2TP53CASP1GLA | |
| SCHEMBL23585338 | 0.93 | L3MBTL1 (0.64) | L3MBTL1SMN1; SMN2TP53CASP1GLA | |
| SCHEMBL21760617 | 0.93 | L3MBTL1 (0.64) | L3MBTL1SMN1; SMN2TP53CASP1GLA | |
| SCHEMBL17393987 | 0.93 | L3MBTL1 (0.64) | L3MBTL1SMN1; SMN2TP53CASP1GLA | |
| SCHEMBL5622378 | 0.93 | TP53 (0.74) | L3MBTL1SMN1; SMN2TP53CASP1GLA | |
| SCHEMBL17394430 | 0.91 | L3MBTL1 (0.60) | L3MBTL1SMN1; SMN2TP53CASP1GLA | |
| SCHEMBL16013130 | 0.85 | L3MBTL1 (0.54) | L3MBTL1SMN1; SMN2TP53CASP1GLA | |
| SCHEMBL15040616 | 0.84 | L3MBTL1 (1.00) | L3MBTL1SMN1; SMN2TP53CASP1DRD2 | |
| SCHEMBL16014701 | 0.82 | L3MBTL1 (0.53) | L3MBTL1SMN1; SMN2TP53CASP1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |