Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.40 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.40 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25344960 | 0.94 | IDO1 (0.42) | IDO1GPR119PKMHRH3EED | |
| SCHEMBL25339942 | 0.93 | IDO1 (0.45) | IDO1GPR119PKMHRH3EED | |
| SCHEMBL25340767 | 0.93 | IDO1 (0.45) | IDO1GPR119PKMHRH3EED | |
| SCHEMBL18148459 | 0.86 | IDO1 (0.47) | IDO1GPR119PKMHRH3TRPM8 | |
| SCHEMBL31738777 | 0.84 | IDO1 (0.37) | IDO1GPR119PKMHRH3EED | |
| SCHEMBL20096619 | 0.84 | IDO1 (0.56) | IDO1GPR119PKMHRH3 | |
| SCHEMBL31738755 | 0.84 | IDO1 (0.37) | IDO1GPR119PKMHRH3EED | |
| SCHEMBL20096860 | 0.83 | IDO1 (0.51) | IDO1GPR119PKMTRPM8TRPV1 | |
| SCHEMBL2346324 | 0.82 | IDO1 (0.47) | IDO1GPR119HRH3 | |
| SCHEMBL25343196 | 0.82 | TRPM8 (0.45) | IDO1GPR119PKMHRH3EED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026283-A1 | COMPOUND FOR SELECTIVELY DEGRADING SMARCA2/4 AND USE THEREOF | 甘李药业股份有限公司 | 2025-02-06 | — | — | WO | disclosed |
| WO-2024156294-A1 | ESTROGEN RECEPTOR PROTEOLYSIS TARGETING CHIMERA COMPOUND AND USE THEREOF | 甘李药业股份有限公司 | 2024-08-02 | — | — | WO | disclosed |
| WO-2023143589-A1 | CEREBLON E3 UBIQUITIN LIGASE INHIBITOR | 甘李药业股份有限公司 | 2023-08-03 | — | — | WO | disclosed |