SCHEMBL25342403

SCHEMBL25342403

CCCN(OCC)C(=O)C1=Cc2ccc(S(=O)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)O)cc2N=C(N)C1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TLR8 Q9NR97 20/20 0.59
▸ TLR7 Q9NYK1 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25347077 0.92 TLR8 (0.60) TLR8TLR7
SCHEMBL25342503 0.91 TLR8 (0.71) TLR8TLR7
SCHEMBL25345229 0.90 TLR8 (0.50) TLR8TLR7
SCHEMBL25344536 0.89 TLR8 (0.54) TLR8TLR7
SCHEMBL25344703 0.87 TLR8 (0.49) TLR8TLR7
SCHEMBL24516972 0.86 TLR8 (0.72) TLR8TLR7
SCHEMBL24516741 0.86 TLR8 (0.72) TLR8TLR7
SCHEMBL25344867 0.85 TLR8 (0.52) TLR8TLR7
SCHEMBL25345573 0.84 TLR8 (0.47) TLR8TLR7
SCHEMBL25345721 0.83 TLR8 (0.49) TLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023154307-A1 ANTIBODY-CONJUGATED 8-SULFONYL-BENZAZEPINE COMPOUNDS AND THEIR USES BOLT BIOTHERAPEUTICS, INC. (US) 2023-08-17 — — WO disclosed
WO-2023154302-A1 MACROMOLECULE-SUPPORTED 8-SULFONYL-BENZAZEPINE COMPOUNDS AND THEIR USES BOLT BIOTHERAPEUTICS, INC. (US) 2023-08-17 — — WO disclosed
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