Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 20/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25344589 | 0.91 | TLR8 (0.60) | TLR8TLR7 | |
| SCHEMBL31506970 | 0.91 | TLR8 (0.47) | TLR8TLR7 | |
| SCHEMBL25342403 | 0.90 | TLR8 (0.59) | TLR8TLR7 | |
| Hydrochloric Acid SCHEMBL25346223 | 0.89 | TLR8 (0.53) | TLR8TLR7 | |
| SCHEMBL25345017 | 0.89 | TLR8 (0.46) | TLR8TLR7 | |
| Hydrochloric Acid SCHEMBL25346222 | 0.89 | TLR8 (0.52) | TLR8TLR7 | |
| SCHEMBL25345721 | 0.87 | TLR8 (0.49) | TLR8TLR7 | |
| SCHEMBL25344867 | 0.84 | TLR8 (0.52) | TLR8TLR7 | |
| SCHEMBL25345573 | 0.83 | TLR8 (0.47) | TLR8TLR7 | |
| SCHEMBL25344703 | 0.82 | TLR8 (0.49) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154307-A1 | ANTIBODY-CONJUGATED 8-SULFONYL-BENZAZEPINE COMPOUNDS AND THEIR USES | BOLT BIOTHERAPEUTICS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023154302-A1 | MACROMOLECULE-SUPPORTED 8-SULFONYL-BENZAZEPINE COMPOUNDS AND THEIR USES | BOLT BIOTHERAPEUTICS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |