Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GUCY1B2 | O75343 | 3/20 | 0.35 |
| ▸ | GUCY1A2 | P33402 | 3/20 | 0.35 |
| ▸ | GUCY1A1 | Q02108 | 3/20 | 0.35 |
| ▸ | GUCY1B1 | Q02153 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30527013 | 1.00 | P2RY12 (0.36) | P2RY12ALDH1A1POLBGUCY1B2GUCY1A2 | |
| SCHEMBL30527018 | 1.00 | P2RY12 (0.36) | P2RY12ALDH1A1POLBGUCY1B2GUCY1A2 | |
| SCHEMBL30527015 | 0.96 | P2RY12 (0.36) | P2RY12ALDH1A1POLBGUCY1B2GUCY1A2 | |
| SCHEMBL30527017 | 0.96 | P2RY12 (0.36) | P2RY12ALDH1A1POLBGUCY1B2GUCY1A2 | |
| SCHEMBL25347237 | 0.96 | P2RY12 (0.36) | P2RY12ALDH1A1POLBGUCY1B2GUCY1A2 | |
| SCHEMBL26056963 | 0.96 | P2RY12 (0.36) | P2RY12ALDH1A1POLBGUCY1B2GUCY1A2 | |
| SCHEMBL26056962 | 0.96 | P2RY12 (0.36) | P2RY12ALDH1A1POLBGUCY1B2GUCY1A2 | |
| SCHEMBL25347247 | 0.91 | GUCY1B2 (0.35) | P2RY12ALDH1A1POLBGUCY1B2GUCY1A2 | |
| SCHEMBL25346112 | 0.90 | GUCY1B2 (0.35) | P2RY12ALDH1A1GUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL25344886 | 0.90 | ALDH1A1 (0.37) | P2RY12ALDH1A1POLBGUCY1B2GUCY1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179065-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2025-06-05 | — | — | US | disclosed |
| WO-2023150203-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179065-A1 | HDAC6 INHIBITORS AND USES THEREOF | HDAC6, HDAC1, HDAC5 | P2RY12 4859/4885ALDH1A1 922/4885POLB 1428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.