Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25253965 | 1.00 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL21071069 | 1.00 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28501706 | 0.98 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL18173574 | 0.89 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9447837 | 0.89 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8958401 | 0.89 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8958557 | 0.89 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8958237 | 0.89 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8958406 | 0.86 | SMN1; SMN2 (0.48) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL20696333 | 0.83 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154307-A1 | ANTIBODY-CONJUGATED 8-SULFONYL-BENZAZEPINE COMPOUNDS AND THEIR USES | BOLT BIOTHERAPEUTICS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023154302-A1 | MACROMOLECULE-SUPPORTED 8-SULFONYL-BENZAZEPINE COMPOUNDS AND THEIR USES | BOLT BIOTHERAPEUTICS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |