Cyclomethycaine

Cyclomethycaine

SCHEMBL25346

C[C@@H]1CCCCN1CCCOC(=O)c1ccc(OC2CCCCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 2/20 1.00
SCN2A Q99250 2/20 1.00
SCN3A Q9NY46 2/20 1.00
HRH3 Q9Y5N1 15/20 0.49
CYP2D6 P10635 2/20 0.48
MAOB P27338 1/20 0.47
HRH2 P25021 1/20 0.47
HRH1 P35367 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclomethycaine SCHEMBL25345 1.00 SCN1A (1.00) SCN1ASCN2ASCN3AHRH3CYP2D6
Cyclomethycaine SCHEMBL634211 0.99 SCN1A (0.98) SCN1ASCN2ASCN3AHRH3CYP2D6
Cyclomethycaine SCHEMBL634210 0.99 SCN1A (0.98) SCN1ASCN2ASCN3AHRH3CYP2D6
Cyclomethycaine SCHEMBL634094 0.96 SCN1A (0.92) SCN1ASCN2ASCN3AHRH3CYP2D6
Cyclomethycaine SCHEMBL634093 0.96 SCN1A (0.92) SCN1ASCN2ASCN3AHRH3CYP2D6
Piperocaine SCHEMBL25713 0.84 SCN1A (1.00) SCN1ASCN2ASCN3AHRH3CYP2D6
Piperocaine SCHEMBL25714 0.84 SCN1A (1.00) SCN1ASCN2ASCN3AHRH3CYP2D6
Piperocaine SCHEMBL503030 0.83 SCN1A (0.98) SCN1ASCN2ASCN3AHRH3CYP2D6
Piperocaine SCHEMBL503032 0.83 SCN1A (0.98) SCN1ASCN2ASCN3AHRH3CYP2D6
Piperocaine SCHEMBL9224611 0.82 SCN1A (0.95) SCN1ASCN2ASCN3AHRH3CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4097 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144801-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MUSCLE CONDITIONS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-05-28 US claimed
US-20260137637-A1 ANESTHETIC AGENT MICRO AND NANO PARTICLES, AND METHODS OF MAKING AND USING THE SAME HAAS ERIC (US) 2026-05-21 US claimed
US-12622873-B2 Composition of matter comprising liposomes embedded in a polymeric matrix and methods of using same YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2026-05-12 US claimed
EP-4735042-A1 MERCERIZED DECELLULARIZED PARTICLES FOR SLOW RELEASE APPLICATIONS AND METHODS THEREOF Spiderwort Biotechnologies Inc. (CA) 2026-05-06 EP claimed
US-20260115156-A1 INJECTABLE COMPOSITION INCLUDING HYDROGEL CONTAINING ANESTHETIC AGENT UNIV KOREA RES & BUS FOUND (KR) 2026-04-30 US claimed
US-20260083666-A1 METHOD OF TREATING DISEASE CREWS THOMAS M (US) 2026-03-26 US claimed
EP-4436552-B1 GASTRO-RETENTIVE ORAL DOSAGE UNIT CONTAINING A LOCAL ANAESTHETIC OREXA B V (NL) 2026-02-04 EP claimed
US-12527756-B2 Anesthetic agent micro and nano particles, and methods of making and using the same HAAS ERIC (US) 2026-01-20 US claimed
WO-2025235864-A1 COATED NEEDLE ADMINISTRATION SYSTEMS EVOLUS, INC. (US) 2025-11-13 WO claimed
US-20250319025-A9 COMPOSITIONS COMPRISING MODIFIED PHOSPHOLIPIDS AND USES THEREOF THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-10-16 US claimed
WO-2001022907-A1 DRUG DELIVERY OF PHASE CHANGING FORMULATION ZARS (US) 2001-04-05 WO claimed
EP-1027015-A1 CONTROLLED RELEASE OF PHARMACEUTICALS IN THE ANTERIOR CHAMBER OF THE EYE Galin, Miles A. (US) 2000-08-16 EP claimed
CN-1251979-A Controlled release of drugs in the anterior chamber of the eye MILES A GALIN (US) 2000-05-03 CN claimed
US-5972326-A Controlled release of pharmaceuticals in the anterior chamber of the eye IOLTECH (FR) 1999-10-26 US claimed
WO-1998041171-A1 CONTROLLED RELEASE OF PHARMACEUTICALS IN THE ANTERIOR CHAMBER OF THE EYE GALIN MILES A (US) 1998-09-24 WO claimed
US-5776952-A Method and composition for topical therapy of back pain and muscle tension AMERICAN PHARMED LABS, INC. (US) 1998-07-07 US claimed
CN-1103288-A Local anaesthetic and its preparing method ZHANG JIE (CN) 1995-06-07 CN claimed
EP-0471135-A2 Compositions, medicaments and methods for the promotion of hair growth Hallam, Kenneth M. (US) 1992-02-19 EP claimed
US-4041174-A INJECTING AN ESTER LOCAL ANESTHETIC ROM-AMER PHARMACEUTICALS, LTD. (US) 1977-08-09 US claimed
US-4022899-A TETRODOXIN, DESOXYTETRODOXIN, AMINOALKYL BENZOATE ASTRA PHARMACEUTICAL PRODUCTS, INC. (US) 1977-05-10 US claimed