Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.56 |
| ▸ | TOP2A | P11388 | 1/20 | 0.56 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.56 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25347749 | 0.83 | SNCA (0.67) | TOP1TOP2ATOP2BMAPK1MAPT | |
| SCHEMBL7120565 | 0.83 | P2RX1 (0.53) | PRSS12MAPK1MAPTP2RX1NPC1 | |
| SCHEMBL12825037 | 0.83 | MEN1 (0.60) | TOP1TOP2ATOP2BPRSS12MAPK1 | |
| SCHEMBL12644447 | 0.83 | HSPD1 (0.64) | TOP1TOP2ATOP2BMAPK1MAPT | |
| SCHEMBL25348176 | 0.83 | TOP1 (0.59) | TOP1TOP2ATOP2BMAPK1MAPT | |
| SCHEMBL25350384 | 0.81 | ABCB1 (0.63) | MAPK1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4355842 | 0.81 | MEN1 (0.57) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL25349190 | 0.81 | MAPT (0.54) | TOP1TOP2ATOP2BMAPK1MAPT | |
| SCHEMBL17295638 | 0.81 | NQO2 (0.60) | TOP1TOP2ATOP2BPRSS12MAPK1 | |
| SCHEMBL11679716 | 0.80 | KMT2A (0.80) | PRSS12MAPK1MAPTP2RX1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023149548-A1 | NOVEL PHARMACEUTICAL COMPOSITION | 国立大学法人富山大学 | 2023-08-10 | — | — | WO | disclosed |