SCHEMBL25349273

SCHEMBL25349273

Cc1cnc2c(C(=O)Nc3cccc(C4(Cc5nncn5C)COC4)c3)cc(CN3CCC[C@H](C)C3)cn12

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.54
▸ CBLC Q9ULV8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25348766 0.93 CBLB (0.55) CBLBCBLC
SCHEMBL25349446 0.86 CBLB (0.57) CBLBCBLC
SCHEMBL30838326 0.85 CBLB (0.55) CBLBCBLC
SCHEMBL25348980 0.85 CBLB (0.56) CBLBCBLC
SCHEMBL31115359 0.81 CBLB (0.68) CBLBCBLC
SCHEMBL25349207 0.81 CBLB (0.68) CBLBCBLC
SCHEMBL31578256 0.81 CBLB (0.62) CBLBCBLC
SCHEMBL25349540 0.79 CBLB (0.70) CBLBCBLC
SCHEMBL25349311 0.78 CBLB (0.54) CBLBCBLC
SCHEMBL30838316 0.78 CBLB (0.55) CBLBCBLC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023151640-A1 HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH BEIGENE , LTD. (KY) 2023-08-17 — — WO disclosed
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