Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25349598 | 1.00 | LMNA (0.42) | LMNAMEN1NPC1USP2S1PR2 | |
| SCHEMBL30545635 | 1.00 | LMNA (0.42) | LMNAMEN1NPC1USP2S1PR2 | |
| SCHEMBL25986886 | 0.89 | LMNA (0.42) | LMNAMEN1NPC1USP2S1PR2 | |
| SCHEMBL25347467 | 0.87 | FOLH1 (0.41) | LMNAMEN1NPC1USP2S1PR2 | |
| SCHEMBL30545614 | 0.87 | FOLH1 (0.41) | LMNAMEN1NPC1USP2S1PR2 | |
| SCHEMBL25986888 | 0.87 | FOLH1 (0.41) | LMNAMEN1NPC1USP2S1PR2 | |
| SCHEMBL25347470 | 0.87 | FOLH1 (0.41) | LMNAMEN1NPC1USP2S1PR2 | |
| SCHEMBL25350144 | 0.87 | MEN1 (0.39) | LMNAMEN1NPC1USP2S1PR2 | |
| SCHEMBL25350140 | 0.87 | MEN1 (0.39) | LMNAMEN1NPC1USP2S1PR2 | |
| SCHEMBL29456903 | 0.82 | MEN1 (0.46) | LMNAMEN1NPC1USP2S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154762-A1 | SQUARAINE FLUOROPHORES | THE GENERAL HOSPITAL CORPORATION (US) | 2023-08-17 | — | — | WO | disclosed |