Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 8/20 | 0.62 |
| ▸ | TMPRSS4 | Q9NRS4 | 8/20 | 0.62 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.62 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.62 |
| ▸ | PLAU | P00749 | 2/20 | 0.59 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | F10 | P00742 | 1/20 | 0.57 |
| ▸ | PLG | P00747 | 1/20 | 0.57 |
| ▸ | PLAT | P00750 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
| ▸ | PNLIP | P16233 | 1/20 | 0.52 |
| ▸ | FADS1 | O60427 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | CHUK | O15111 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25349562 | 0.88 | TMPRSS4 (0.72) | P2RX1TMPRSS4P2RX4P2RX7MEN1 | |
| SCHEMBL23752552 | 0.85 | JAK2 (0.60) | P2RX1TMPRSS4P2RX4P2RX7HSPD1 | |
| SCHEMBL330564 | 0.84 | P2RX1 (0.76) | P2RX1TMPRSS4P2RX4P2RX7PLAU | |
| SCHEMBL11594959 | 0.80 | P2RX1 (0.65) | P2RX1P2RX4P2RX7PLAUALOX15 | |
| SCHEMBL7172686 | 0.80 | TMPRSS4 (0.77) | P2RX1TMPRSS4P2RX4P2RX7PLAU | |
| SCHEMBL25348129 | 0.78 | KLKB1 (0.61) | P2RX1TMPRSS4PLAUKLKB1F2 | |
| SCHEMBL18290067 | 0.77 | PNLIP (0.67) | P2RX1TMPRSS4P2RX4P2RX7PLAU | |
| SCHEMBL1841753 | 0.77 | P2RX1 (0.54) | P2RX1TMPRSS4P2RX4P2RX7PLAU | |
| SCHEMBL130143 | 0.77 | P2RX1 (1.00) | P2RX1TMPRSS4P2RX4P2RX7KLKB1 | |
| SCHEMBL12644623 | 0.76 | KCNK3 (0.61) | HSPD1HSPE1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023149548-A1 | NOVEL PHARMACEUTICAL COMPOSITION | 国立大学法人富山大学 | 2023-08-10 | — | — | WO | disclosed |