Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.59 |
| ▸ | LCK | P06239 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RGS12 | O14924 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155333 | 1.00 | EGFR (0.70) | EGFRAKR1B1LCKPOLBMEN1 | |
| SCHEMBL30452045 | 1.00 | EGFR (0.70) | EGFRAKR1B1LCKPOLBMEN1 | |
| SCHEMBL29354171 | 1.00 | EGFR (0.70) | EGFRAKR1B1LCKPOLBMEN1 | |
| Gentisic Acid SCHEMBL29793329 | 0.89 | CA1 (0.69) | EGFRAKR1B1LCKMEN1KMT2A | |
| Benzoic Acid SCHEMBL3326836 | 0.88 | EGFR (0.57) | EGFRAKR1B1LCKMEN1KMT2A | |
| SCHEMBL19554162 | 0.85 | HSD17B10 (0.62) | EGFRLCKPOLBMEN1KMT2A | |
| SCHEMBL156238 | 0.84 | TYR (0.60) | EGFRAKR1B1POLBMEN1KMT2A | |
| SCHEMBL18321224 | 0.84 | EGFR (0.53) | EGFRLCKHPGDALDH1A1CYP2C9 | |
| SCHEMBL29419312 | 0.84 | TYR (0.60) | EGFRAKR1B1POLBMEN1KMT2A | |
| Cysteine SCHEMBL2119561 | 0.82 | EGFR (0.52) | EGFRAKR1B1LCKPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110257264-A1 | USE OF 2,5-DIHYDROXYBENZENE DERIVATIVES FOR TREATING ACTINIC KERATOSIS | ACTION MEDICINES (ES) | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257264-A1 | USE OF 2,5-DIHYDROXYBENZENE DERIVATIVES FOR TREATING ACTINIC KERATOSIS | CYP8B1, DERA, KRT18 | EGFR 3265/4885AKR1B1 4/4885LCK 1873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.