Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 3/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035932 | 0.94 | HSD17B10 (0.70) | HSD17B10KDM4EPOLBABL1MAPT | |
| SCHEMBL30335932 | 0.85 | POLB (0.73) | HSD17B10KDM4EPOLBABL1MAPT | |
| SCHEMBL3296862 | 0.85 | POLB (0.73) | HSD17B10KDM4EPOLBABL1MAPT | |
| SCHEMBL155333 | 0.85 | EGFR (0.70) | HSD17B10KDM4EPOLBMAPTEGFR | |
| SCHEMBL29354171 | 0.85 | EGFR (0.70) | HSD17B10KDM4EPOLBMAPTEGFR | |
| SCHEMBL2535192 | 0.85 | EGFR (0.70) | HSD17B10KDM4EPOLBMAPTEGFR | |
| SCHEMBL30452045 | 0.85 | EGFR (0.70) | HSD17B10KDM4EPOLBMAPTEGFR | |
| SCHEMBL4081034 | 0.82 | MTNR1A (0.55) | HSD17B10KDM4EPOLBMAPTRECQL | |
| SCHEMBL8772666 | 0.80 | MTNR1A (0.57) | HSD17B10KDM4EPOLBABL1MAPT | |
| SCHEMBL4034916 | 0.79 | MTNR1A (0.56) | HSD17B10KDM4EPOLBMAPTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452095-B1 | SIMMONDSIN FORMULATION | Van Den Driessche Herman (BE) | 2021-04-07 | — | — | EP | disclosed |
| EP-3452095-A2 | SIMMONDSIN FORMULATION | Van den Driessche, Herman (BE) | 2019-03-13 | — | — | EP | disclosed |
| WO-2017191501-A2 | SIMMONDSIN FORMULATION | D'OOSTERLYNCK ANDRÉ (BE) | 2017-11-09 | — | — | WO | disclosed |