Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581312 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TP53LMNAMAPK1 | |
| SCHEMBL8710732 | 0.86 | ALDH1A1 (0.39) | ALDH1A1TP53LMNAMAPK1 | |
| SCHEMBL13496008 | 0.77 | — | — | |
| SCHEMBL5692486 | 0.77 | — | — | |
| SCHEMBL20768164 | 0.76 | ALDH1A1 (0.35) | ALDH1A1TP53LMNAMAPK1 | |
| SCHEMBL4391770 | 0.65 | ALDH1A1 (0.35) | ALDH1A1TP53LMNA | |
| SCHEMBL1536062 | 0.65 | ALDH1A1 (0.38) | ALDH1A1TP53LMNA | |
| SCHEMBL4646956 | 0.65 | ALDH1A1 (0.38) | ALDH1A1TP53LMNA | |
| SCHEMBL3226475 | 0.64 | — | — | |
| SCHEMBL8533882 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246988-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2024-07-25 | — | — | US | disclosed |
| CN-112300172-B | Bruton tyrosine kinase inhibitors | 比奥根MA公司 | 2024-01-16 | — | — | CN | disclosed |
| US-20230123612-A1 | Productivity and Bioproduct Formation in Phototropin Knock/Out Mutants in Microalgae | TRIAD NATIONAL SECURITY, LLC | 2023-04-20 | — | — | US | disclosed |
| US-20230046457-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | BIOGEN MA INC. | 2023-02-16 | — | — | US | disclosed |
| EP-3887533-B1 | METHOD FOR THE FERMENTATIVE PRODUCTION OF L-LYSINE | EVONIK OPERATIONS GMBH (DE) | 2023-01-04 | — | — | EP | disclosed |
| EP-3628742-B1 | METHOD FOR THE FERMENTATIVE PRODUCTION OF L-LYSINE | EVONIK OPERATIONS GMBH (DE) | 2022-07-20 | — | — | EP | disclosed |
| US-11198895-B2 | Method for the fermentative production of L-lysine using an L-lysine excreting bacterium of the species Corynebacterium glutamicum having a completely or partly deleted WHIB4 gene | EVONIK OPERATIONS GMBH (DE) | 2021-12-14 | — | — | US | disclosed |
| US-20210355515-A1 | METHOD FOR THE FERMENTATIVE PRODUCTION OF L-LYSINE USING AN L-LYSINE EXCRETING BACTERIUM OF THE SPECIES CORYNEBACTERIUM GLUTAMICUM HAVING A COMPLETELY OR PARTLY DELETED WHIB4 GENE | EVONIK OPERATIONS GMBH (DE) | 2021-11-18 | — | — | US | disclosed |
| EP-3887533-A1 | METHOD FOR THE FERMENTATIVE PRODUCTION OF L-LYSINE USING AN L-LYSINE EXCRETING BACTERIUM OF THE SPECIES CORYNEBACTERIUM GLUTAMICUM HAVING A COMPLETELY OR PARTLY DELETED WHIB4 GENE | Evonik Operations GmbH (DE) | 2021-10-06 | — | — | EP | disclosed |
| CN-106191146-B | Method for producing L-amino acids using bacteria of the family Enterobacteriaceae having attenuated expression of the gshA gene | 味之素株式会社 | 2021-08-17 | — | — | CN | disclosed |
| EP-0262463-B1 | NOVEL AUREOBASIDIUM SP. MICROORGANISMS, METHOD FOR PREPARING ERYTHRITOL WITH THE SAME | Director of National Food Research Institute Ministry of Agriculture Forestry and Fisheries (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5036011-A | Biosynthesis from sugars | DIRECTOR OF NATIONAL FOOD RESEARCH INSTITUTE, MINISTRY OF AGRICULTURE, FORESTRY AND FISHERIES (JP) | 1991-07-30 | — | — | US | disclosed |
| US-4939091-A | Biosynthesis, fermentation of sugars | DIRECTOR OF NATIONAL FOOD RESEARCH INSTITUTE, MINISTRY OF AGRICULTURE, FORESTRY AND FISHERIES (JP) | 1990-07-03 | — | — | US | disclosed |
| US-4654334-A | ANIMAL FEEDS | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1987-03-31 | — | — | US | disclosed |
| US-4478935-A | FERMENTATION NUTRIENTS TO PRODUCE POLYETHER ANTIBIOTICS, ADDING WATER SOLUBLE MANGANESE SALT TO GIVE COMPLEX | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1984-10-23 | — | — | US | disclosed |
| US-4189537-A | Process of producing antibiotic BL580Δ with Streptomyces hygroscopicus | AMERICAN CYANAMID COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| EP-0002535-A2 | Process for the preparation of 21-hydroxy-20-methyl pregnanes | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-06-27 | — | — | EP | disclosed |
| US-4138481-A | ANTICOCCIDIAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-4132779-A | Antibiotic BL580 Zeta and use thereof as anticoccidial agent | AMERICAN CYANAMID COMPANY (US) | 1979-01-02 | — | — | US | disclosed |
| US-4066510-A | ASSAY FOR MUTAGENESIS IN DIPLOID HUMAN LYMPHOBLASTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1978-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246988-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | BTK, ABL1, SYK | ALDH1A1 4783/4885TP53 1014/4885LMNA 3697/4885 |
| US-20230046457-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | BTK, ABL1, SYK | ALDH1A1 4783/4885TP53 1014/4885LMNA 3697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.