Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | VHL | P40337 | 1/20 | 0.31 |
| ▸ | ELOC | Q15369 | 1/20 | 0.31 |
| ▸ | ELOB | Q15370 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 4/20 | 0.31 |
| ▸ | CA1 | P00915 | 4/20 | 0.31 |
| ▸ | CA9 | Q16790 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25356462 | 1.00 | KDM4E (0.33) | KDM4EALDH1A1EPHX2PREPSLC6A2 | |
| SCHEMBL3393951 | 0.79 | KDM1A (0.34) | SLC6A4SLC6A3VHLELOCELOB | |
| SCHEMBL25646277 | 0.78 | CARM1 (0.41) | KDM4EALDH1A1EPHX2MAPT | |
| SCHEMBL19643519 | 0.77 | AR (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19643521 | 0.77 | AR (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5390652 | 0.74 | NAAA (0.40) | EPHX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5390650 | 0.74 | NAAA (0.40) | EPHX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18042524 | 0.73 | — | — | |
| SCHEMBL18042525 | 0.73 | — | — | |
| SCHEMBL5381573 | 0.72 | FURIN (0.40) | EPHX2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |