Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30426682 | 0.84 | CYP11B2 (0.47) | CYP11B2CYP11B1MAPTELANEG6PD | |
| SCHEMBL25230765 | 0.84 | CYP11B2 (0.47) | CYP11B2CYP11B1MAPTELANEG6PD | |
| SCHEMBL29364970 | 0.79 | CYP11B2 (0.47) | CYP11B2CYP11B1MAPTELANEG6PD | |
| SCHEMBL25206285 | 0.79 | CYP11B2 (0.47) | CYP11B2CYP11B1MAPTELANEG6PD | |
| SCHEMBL29052562 | 0.75 | CYP11B2 (0.45) | CYP11B2CYP11B1MAPTELANEG6PD | |
| SCHEMBL25206359 | 0.74 | MAPT (0.47) | CYP11B2CYP11B1MAPTELANEG6PD | |
| SCHEMBL30663914 | 0.71 | CYP11B2 (0.71) | CYP11B2CYP11B1DPP4DPP8ATM | |
| SCHEMBL8209154 | 0.71 | CYP11B2 (0.71) | CYP11B2CYP11B1DPP4DPP8ATM | |
| SCHEMBL25362130 | 0.69 | MAPT (0.43) | CYP11B2CYP11B1MAPTG6PDPTGS2 | |
| SCHEMBL30784323 | 0.69 | MAPT (0.43) | CYP11B2CYP11B1MAPTG6PDPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023159155-A1 | INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) AND USES THEREOF | PIVALENT THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |