Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 14/20 | 0.60 |
| ▸ | AKT1 | P31749 | 1/20 | 0.60 |
| ▸ | AKT2 | P31751 | 1/20 | 0.60 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.60 |
| ▸ | PIK3CB | P42338 | 19/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.53 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.53 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.53 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | DDX6 | P26196 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | CSK | P41240 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27121826 | 0.89 | PIK3CA (0.61) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL25358740 | 0.88 | PIK3CA (0.60) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL25364344 | 0.88 | PIK3CA (0.63) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL27122136 | 0.84 | PIK3CA (0.45) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL32688088 | 0.83 | PIK3CA (0.63) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL32688217 | 0.82 | PIK3CA (0.57) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL27116444 | 0.81 | PIK3CA (0.63) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL12700775 | 0.80 | PIK3CB (0.82) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL27116502 | 0.80 | PIK3CA (0.55) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL25360705 | 0.80 | PIK3CA (0.51) | PIK3CAAKT1AKT2AKT3PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023159155-A1 | INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) AND USES THEREOF | PIVALENT THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |