⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6546575 | 0.98 | ALDH1A1 (0.47) | — | |
| Bromide SCHEMBL27470986 | 0.98 | TSHR (0.46) | — | |
| Pyridine SCHEMBL28090960 | 0.89 | ALDH1A1 (0.46) | — | |
| SCHEMBL8908954 | 0.84 | — | — | |
| SCHEMBL3807178 | 0.84 | TSHR (0.39) | — | |
| SCHEMBL8847499 | 0.80 | KDM4E (0.36) | — | |
| SCHEMBL11680374 | 0.80 | — | — | |
| SCHEMBL9978846 | 0.80 | — | — | |
| SCHEMBL4600538 | 0.80 | — | — | |
| SCHEMBL6338128 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-115666567-A | Furin inhibitors for the treatment of coronavirus infection | BP资产V股份有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-113061149-B | Preparation method of interchelated ligand, hydroformylation catalyst and dihydric alcohol | 万华化学集团股份有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-113061149-A | Preparation method of interchelated ligand, hydroformylation catalyst and dihydric alcohol | 万华化学集团股份有限公司 | 2021-07-02 | — | — | CN | claimed |
| CN-101675061-A | pyrrolo-N-heterocyclic derivatives, process for their preparation and their use in medicine | SHANGHAI HENGRUI PHARM CO LTD | 2010-03-17 | — | — | CN | claimed |
| CN-101049296-A | Nitric ester derivatives and use in treatment of urinary incontinence and other diseases | NICOX SA (FR) | 2007-10-10 | — | — | CN | claimed |
| EP-1429807-A2 | COMBINATION OF A NSAID AND A PDE-4 INHIBITOR | ALTANA Pharma AG (DE) | 2004-06-23 | — | — | EP | claimed |
| WO-2003024489-A2 | COMBINATION OF A NSAID AND A PDE-4 INHIBITOR | ALTANA PHARMA AG (DE) | 2003-03-27 | — | — | WO | claimed |
| EP-1017380-A1 | TOPICAL NON-STEROIDAL ANTI-INFLAMMATORY DRUG COMPOSITION | Biocontrol Incorporated (US) | 2000-07-12 | — | — | EP | claimed |
| EP-0821587-A4 | COMPOSITIONS, KITS, AND METHODS FOR ADMINISTRATION OF ANTILIPEMIC AND ANTI-PLATELET AGGREGATION DRUGS | LIPOPROTEIN TECHNOLOGIES INC (US) | 1999-05-19 | — | — | EP | claimed |
| US-5308861-A | Tetrapyrole compounds | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1994-05-03 | — | — | US | claimed |
| US-5011852-A | Indoleacetic derivatives, alcohol free | APPLIED ANALYTICAL INDUSTRIES, INC. (US) | 1991-04-30 | — | — | US | claimed |
| EP-0079623-B1 | PROCESS FOR THE PREPARATION OF 1H-PYRROLE-2-ACETIC ESTERS | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1985-08-21 | — | — | EP | claimed |
| US-4493935-A | SAPONIFICATION IH-PYRROL-2-ACETONITRILE (OR-ACETAMIDE), THEN 7AR-) | RUTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1985-01-15 | — | — | US | claimed |
| US-4465843-A | ALKYLATION, SAPONIFICATION, DECARBOXYLATION, AND BENZOYLATION OF 3,S-SIETHOXYCARBONYL-4-METHYL-2-PYRROLE ACETATE | LABORATORIES PHARMEDICAL SA (LU) | 1984-08-14 | — | — | US | claimed |
| EP-0010553-B1 | PROCESS OF REDUCING A LOWERALKYL 1-LOWERALKYL-PYRROLE-2-GLYOXYLATE TO A LOWERALKYL 1-LOWERALKYL-PYRROLE-2-ACETATE | McNeilab, Inc. (US) | 1983-05-18 | — | — | EP | claimed |
| WO-1982001552-A1 | PROCESS FOR PRODUCING SUBSTITUTED PYRROLES | ETHYL CORP (US) | 1982-05-13 | — | — | WO | claimed |
| EP-0051442-A1 | Process for producing substituted pyrroles | ETHYL CORPORATION (US) | 1982-05-12 | — | — | EP | claimed |
| US-4284562-A | Process for preparing pyrrole-2-acetic acids | MCNEILAB, INC. (US) | 1981-08-18 | — | — | US | claimed |
| US-3957818-A | PREPARATION OF PYRROLE-2-ACETIC ACID DERIVATIVES | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-05-18 | — | — | US | claimed |