SCHEMBL2535927

SCHEMBL2535927

CC1(C)OB(c2cnn(CC3OCCO3)c2)OC1(C)C

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.58
IKBKE Q14164 1/20 0.33
TBK1 Q9UHD2 1/20 0.33
FAAH O00519 1/20 0.33
LPL P06858 8/20 0.33
LIPG Q9Y5X9 8/20 0.33
F11 P03951 1/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
DGAT1 O75907 1/20 0.30
IRAK4 Q9NWZ3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19552312 0.84 FFAR1 (0.53) FFAR1LPLLIPGF11DGAT1
SCHEMBL31030386 0.84 FFAR1 (0.56) FFAR1LPLLIPGF11IRAK4
SCHEMBL15334053 0.83 FFAR1 (0.49) FFAR1IRAK4
SCHEMBL15359061 0.83 FFAR1 (0.49) FFAR1IRAK4
SCHEMBL15377247 0.83 FFAR1 (0.49) FFAR1IRAK4
SCHEMBL1559915 0.82 FFAR1 (0.57) FFAR1LPLLIPGF11IRAK4
SCHEMBL15376095 0.81 FFAR1 (0.50) FFAR1CNR1CNR2
SCHEMBL15377147 0.81 FFAR1 (0.50) FFAR1CNR1CNR2
SCHEMBL2513372 0.81 FFAR1 (0.50) FFAR1CNR1CNR2
SCHEMBL18985768 0.81 FFAR1 (0.56) FFAR1LPLLIPGF11IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4236932-B1 DEGRADANT COMPOUND IN A MEDICAMENT VISUS THERAPEUTICS INC (US) 2026-01-07 EP claimed
EP-3946183-B1 A FLOW CONTROL DEVICE FOR DELIVERING AN OPHTHALMIC FORMULATION TEARCLEAR CORP (US) 2025-10-29 EP claimed
EP-3270892-B1 FIXED DOSE COMBINATION OF BRIMONIDINE AND TIMOLOL ALLERGAN INC (US) 2024-04-10 EP claimed
EP-3179982-B1 METHOD OF INCREASING BIOAVAILABILITY AND/OR PROLONGING OPHTHALMIC ACTION OF A DRUG SUN PHARMA ADVANCED RES CO LTD (IN) 2023-07-19 EP claimed
US-20230072164-A1 GRANULAR PHARMACEUTICAL PRODUCT FOR ORAL ADMINISTRATION FROM A PRE-FILLED STRAW AND METHOD OF MANUFACTURING SUCH PHARMACEUTICAL PRODUCT ALTERNO LABS D.O.O. (SI) 2023-03-09 US disclosed
EP-4096642-A1 GRANULAR PHARMACEUTICAL PRODUCT FOR ORAL ADMINISTRATION FROM A PRE-FILLED STRAW AND METHOD OF MANUFACTURING SUCH PHARMACEUTICAL PRODUCT Alterno Labs d.o.o. (SI) 2022-12-07 EP disclosed
US-11365199-B2 Pyrazole compounds as modulators of FSHR and uses thereof MERCK PATENT GMBH (DE) 2022-06-21 US disclosed
EP-3013832-B1 PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF MERCK PATENT GMBH (DE) 2020-11-04 EP disclosed
EP-2714677-B1 PYRIDINE-AND PYRAZINE DERIVATIVES MERCK PATENT GMBH (DE) 2018-08-22 EP disclosed
US-20160152626-A1 PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF MERCK PATENT GMBH (DE) 2016-06-02 US disclosed
US-20160152626-A1 PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF MERCK PATENT GMBH (DE) 2016-06-02 US disclosed
US-9273029-B2 Pyridine-and pyrazine derivatives MERCK PATENT GMBH (DE) 2016-03-01 US disclosed
US-8455484-B2 Selected inhibitors of protein tyrosine kinase activity METHYLGENE INC. (CA) 2013-06-04 US disclosed
WO-2012161877-A1 PYRIDINE-AND PYRAZINE DERIVATIVES MERCK PATENT GMBH (DE) 2012-11-29 WO disclosed
WO-2011127567-A1 INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY METHYLGENE INC. (CA) 2011-10-20 WO disclosed
WO-2011127565-A1 INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY AND USE THEREOF TO TREAT OPHTHALMIC DISORDERS METHYLGENE INC. (CA) 2011-10-20 WO disclosed
US-20110257100-A1 Inhibitors of Protein Tyrosine Kinase Activity METHYLGENE INC. (CA) 2011-10-20 US disclosed
US-20110257100-A1 Inhibitors of Protein Tyrosine Kinase Activity METHYLGENE INC. (CA) 2011-10-20 US disclosed
US-20110257175-A1 Selected Inhibitors of Protein Tyrosine Kinase Activity METHYLGENE INC. (CA) 2011-10-20 US disclosed
US-20110257100-A1 Inhibitors of Protein Tyrosine Kinase Activity METHYLGENE INC. (CA) 2011-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11365199-B2 Pyrazole compounds as modulators of FSHR and uses thereof FSHR, GNRHR, LHCGR FFAR1 86/4885IKBKE 2394/4885TBK1 909/4885
US-20160152626-A1 PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR FFAR1 86/4885IKBKE 2394/4885TBK1 909/4885
US-20110257100-A1 Inhibitors of Protein Tyrosine Kinase Activity ERBB2, ABL1, FLT1 FFAR1 2744/4885IKBKE 231/4885TBK1 179/4885
US-20110257175-A1 Selected Inhibitors of Protein Tyrosine Kinase Activity ABL1, PRKDC, PRKACA FFAR1 3849/4885IKBKE 345/4885TBK1 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.