Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | PARG | Q86W56 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690313 | 1.00 | DHODH (0.45) | DHODHEGFRBRD4KDM4EALDH1A1 | |
| SCHEMBL30690356 | 0.89 | HTT (0.37) | DHODHKDM4EALDH1A1TDP1MAPT | |
| SCHEMBL29139169 | 0.89 | HTT (0.37) | DHODHKDM4EALDH1A1TDP1MAPT | |
| SCHEMBL25359989 | 0.88 | DHODH (0.38) | DHODHL3MBTL1 | |
| SCHEMBL30495146 | 0.88 | DHODH (0.38) | DHODHL3MBTL1 | |
| SCHEMBL30495268 | 0.88 | EGFR (0.48) | DHODHEGFRBRD4KDM4EADORA2A | |
| SCHEMBL25356259 | 0.88 | EGFR (0.48) | DHODHEGFRBRD4KDM4EADORA2A | |
| SCHEMBL25360145 | 0.87 | DHODH (0.41) | DHODHKDM4EALDH1A1ADORA2AADORA2B | |
| SCHEMBL25358297 | 0.87 | CYP2C9 (0.42) | DHODHKDM4EALDH1A1MAPT | |
| SCHEMBL30495073 | 0.87 | CYP2C9 (0.42) | DHODHKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015341-A1 | PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | HINOVA PHARMACEUTICALS INC (CN) | 2026-01-15 | — | — | US | disclosed |
| EP-4553075-A1 | PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024008122-A1 | PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 海创药业股份有限公司 | 2024-01-11 | — | — | WO | disclosed |
| CN-117362281-A | PI3K inhibitor and preparation method and application thereof | 海创药业股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| WO-2023159155-A1 | INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) AND USES THEREOF | PIVALENT THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260015341-A1 | PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | PIK3CA, PIK3R4, PIK3R1 | DHODH 1642/4885EGFR 686/4885BRD4 2130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.