Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | CTSE | P14091 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25361414 | 1.00 | TRPV3 (0.50) | TRPV3PDE4BHTTALOX5APFEN1 | |
| SCHEMBL30496025 | 1.00 | TRPV3 (0.50) | TRPV3PDE4BHTTALOX5APFEN1 | |
| SCHEMBL31208013 | 0.94 | TRPV3 (0.51) | TRPV3PDE4BHTTALOX5APFEN1 | |
| SCHEMBL25363244 | 0.94 | TRPV3 (0.51) | TRPV3PDE4BHTTALOX5APFEN1 | |
| SCHEMBL26024707 | 0.94 | TRPV3 (0.51) | TRPV3PDE4BHTTALOX5APFEN1 | |
| SCHEMBL22119681 | 0.93 | HTT (0.49) | TRPV3HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL30087081 | 0.93 | HTT (0.49) | TRPV3HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL25366217 | 0.87 | TRPV3 (0.52) | TRPV3PDE4BHTTMEN1KMT2A | |
| SCHEMBL31208026 | 0.87 | TRPV3 (0.52) | TRPV3PDE4BHTTMEN1KMT2A | |
| SCHEMBL26025833 | 0.87 | TRPV3 (0.52) | TRPV3PDE4BHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444305-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |