Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21389659 | 0.87 | KDM4E (0.53) | KDM4ELMNAEPHX2ESR1POLB | |
| SCHEMBL15076059 | 0.87 | KDM4E (0.53) | KDM4ELMNAEPHX2ESR1ALDH1A1 | |
| SCHEMBL19786751 | 0.87 | KDM4E (0.53) | KDM4ELMNAEPHX2ESR1POLB | |
| SCHEMBL25361465 | 0.87 | KDM4E (0.53) | KDM4ELMNAEPHX2ESR1ALDH1A1 | |
| SCHEMBL5395258 | 0.83 | KDM4E (0.56) | KDM4ELMNAEPHX2ESR1ALDH1A1 | |
| SCHEMBL11064769 | 0.81 | KDM4E (0.61) | KDM4ELMNAEPHX2ESR1ALDH1A1 | |
| SCHEMBL11064771 | 0.81 | KDM4E (0.61) | KDM4ELMNAEPHX2ESR1ALDH1A1 | |
| SCHEMBL26031407 | 0.80 | TDP1 (0.50) | KDM4ELMNAEPHX2ESR1KMT2A | |
| SCHEMBL19186278 | 0.80 | TDP1 (0.50) | KDM4ELMNAEPHX2ESR1KMT2A | |
| SCHEMBL14392991 | 0.80 | KDM4E (0.59) | KDM4ELMNAEPHX2ESR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156601-A1 | DIAGNOSTICS FOR DETECTING ECTO-5'-NUCLEOTIDASE (CD73) | Westfälische Wilhelms-Universität Münster (DE) | 2023-08-24 | — | — | WO | disclosed |