Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 3/20 | 0.45 |
| ▸ | TLR1 | Q15399 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | FPR3 | P25089 | 4/20 | 0.44 |
| ▸ | FPR2 | P25090 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19186278 | 1.00 | TDP1 (0.50) | TDP1KDM4ELMNAEPHX2MAOA | |
| SCHEMBL19601252 | 0.94 | KDM4E (0.49) | TDP1KDM4ELMNAEPHX2TLR2 | |
| SCHEMBL9924681 | 0.94 | KDM4E (0.49) | TDP1KDM4ELMNAEPHX2TLR2 | |
| SCHEMBL21389659 | 0.81 | KDM4E (0.53) | KDM4ELMNAEPHX2ESR1 | |
| SCHEMBL19786751 | 0.81 | KDM4E (0.53) | KDM4ELMNAEPHX2ESR1 | |
| SCHEMBL13107792 | 0.80 | KDM4E (0.41) | KDM4ELMNATLR2TLR1ESR1 | |
| SCHEMBL25361995 | 0.80 | KDM4E (0.54) | TDP1KDM4ELMNAEPHX2ESR1 | |
| SCHEMBL25361465 | 0.79 | KDM4E (0.53) | KDM4ELMNAEPHX2TLR2TLR1 | |
| SCHEMBL15076059 | 0.79 | KDM4E (0.53) | KDM4ELMNAEPHX2TLR2TLR1 | |
| SCHEMBL5395258 | 0.78 | KDM4E (0.56) | KDM4ELMNAEPHX2TLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156601-A1 | DIAGNOSTICS FOR DETECTING ECTO-5'-NUCLEOTIDASE (CD73) | Westfälische Wilhelms-Universität Münster (DE) | 2023-08-24 | — | — | WO | disclosed |