SCHEMBL25362802

SCHEMBL25362802

CC(CCCP(=O)(O)CC(CCC(=O)O)C(=O)O)c1ccccc1.CCC(CCP(=O)(O)CC(CCC(=O)O)C(=O)O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.46
GRM3 Q14832 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26602760 0.91 GRM3 (0.51) FOLH1GRM3
SCHEMBL1373545 0.91 GRM3 (0.54) FOLH1GRM3
SCHEMBL1377066 0.91 FOLH1 (0.54) FOLH1GRM3
SCHEMBL25362800 0.88 FOLH1 (0.36) FOLH1GRM3
SCHEMBL2369323 0.79 FOLH1 (0.48) FOLH1GRM3
SCHEMBL2368585 0.79 FOLH1 (0.48) FOLH1GRM3
SCHEMBL2368582 0.77 FOLH1 (0.46) FOLH1GRM3
SCHEMBL2369322 0.77 FOLH1 (0.46) FOLH1GRM3
SCHEMBL28021364 0.74 GABBR2 (0.42)
SCHEMBL1374848 0.74 FOLH1 (0.59) FOLH1GRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023154939-A2 GCPII INHIBITION FOR THE TREATMENT OF SARCOPENIA AND AGING THE JOHNS HOPKINS UNIVERSITY (US) 2023-08-17 WO claimed
WO-2023154939-A2 GCPII INHIBITION FOR THE TREATMENT OF SARCOPENIA AND AGING THE JOHNS HOPKINS UNIVERSITY (US) 2023-08-17 WO disclosed