⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11750040 | 1.00 | SIGMAR1 (0.43) | — | |
| SCHEMBL203650 | 1.00 | SIGMAR1 (0.43) | — | |
| Hydrochloric Acid SCHEMBL3675933 | 0.96 | SIGMAR1 (0.42) | — | |
| Water SCHEMBL29754132 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL1641825 | 0.96 | — | — | |
| SCHEMBL1421599 | 0.90 | PLG (0.44) | — | |
| SCHEMBL4432479 | 0.90 | SIGMAR1 (0.50) | — | |
| SCHEMBL24273689 | 0.87 | SIGMAR1 (0.37) | — | |
| SCHEMBL3822200 | 0.87 | SIGMAR1 (0.37) | — | |
| SCHEMBL4891777 | 0.86 | SIGMAR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117983168-B | Charging intelligent regulation's cyclopropylethyl amide production reation kettle | 江苏飞宇医药科技股份有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-117983168-A | Charging intelligent regulation's cyclopropylethyl amide production reation kettle | 江苏飞宇医药科技股份有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-117398960-B | Cyclopropylethyl amide production reaction kettle with quantitative feeding structure | 江苏飞宇医药科技股份有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-117398960-A | Cyclopropylethyl amide production reaction kettle with quantitative feeding structure | 江苏飞宇医药科技股份有限公司 | 2024-01-16 | — | — | CN | claimed |
| CN-219785173-U | Cyclopropylethyl amide preparation centrifuge | 江西华飞医药科技有限公司 | 2023-10-03 | — | — | CN | claimed |
| WO-2023147513-A2 | COMPOSITIONS OF AUTOPHAGY MODULATING AGENTS AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2023-08-03 | — | — | WO | claimed |
| CN-114436875-B | Preparation method of cyclopropylethyl amide | 江苏飞宇医药科技股份有限公司 | 2023-05-12 | — | — | CN | claimed |
| WO-2023070483-A1 | PROCESSES OF MAKING 3-FLUORO-5- ( ( (1R, 2S, 2aS) -1, 2, 3, 3, 4, 4-HEXAFLUORO-2A-HYDROXY-2, 2A, 3, 4-TETRAHYDRO-1H-CYCLOPENTA [CD] INDEN-7-YL) -OXY) -BENZONITRILE AND POLYMORPHS THEREOF | NIKANG THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | claimed |
| WO-2023060458-A1 | PROCESSES OF MAKING 3-FLUORO-5- ( ( (1S, 2AR) -1, 3, 3, 4, 4-PENTAFLUORO-2A-HYDROXY-2, 2A, 3, 4-TETRAHYDRO-1H-CYCLOPENTA [CD] INDEN-7-YL) OXY) -BENZONITRILE AND POLYMORPHS THEREOF | NIKANG THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | claimed |
| WO-2023060431-A1 | PROCESSES OF MAKING 3-FLUORO-5- ( ( (1S, 2AR) -1, 3, 3, 4, 4-PENTAFLUORO-2A-HYDROXY-2, 2A, 3, 4-TETRAHYDRO-1H-CYCLOPENTA [CD] INDEN-7-YL) OXY) -BENZONITRILE AND POLYMORPHS THEREOF | NIKANG THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | claimed |
| EP-1648874-A2 | PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2006-04-26 | — | — | EP | claimed |
| WO-2006034341-A2 | PYRIDAZINE DERIVATIVES FOR INHIBITING HUMAN STEAROYL-COA-DESATURASE | XENON PHARMACEUTICALS INC. (CA) | 2006-03-30 | — | — | WO | claimed |
| WO-2006034279-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2006-03-30 | — | — | WO | claimed |
| WO-2006034338-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS MEDIATORS OF STEAROYL-COA DESATURASE | XENON PHARMACEUTICALS INC. (CA) | 2006-03-30 | — | — | WO | claimed |
| WO-2006014168-A1 | NICOTINAMIDE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2006-02-09 | — | — | WO | claimed |
| US-20050119251-A1 | Nicotinamide derivatives and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2005-06-02 | — | — | US | claimed |
| US-20050065143-A1 | Pyridazine derivatives and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2005-03-24 | — | — | US | claimed |
| WO-2005011655-A2 | PYRIDAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2005-02-10 | — | — | WO | claimed |
| WO-2005011656-A2 | PYRIDYL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2005-02-10 | — | — | WO | claimed |
| EP-0582829-B1 | 9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines as antibiotic agents | AMERICAN CYANAMID CO (US) | 2001-09-12 | — | — | EP | claimed |