Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10515631 | 0.85 | DPP4 (0.43) | DPP4SMN1; SMN2MAPTMAPK1CASP3 | |
| SCHEMBL10132043 | 0.84 | AGBL2 (0.50) | AGBL2DPP4SMN1; SMN2MAPTMAOB | |
| SCHEMBL10515506 | 0.83 | DPP4 (0.41) | DPP4SMN1; SMN2MAPTMAOBMAPK1 | |
| SCHEMBL26091014 | 0.83 | CYP2C19 (0.42) | DPP4SMN1; SMN2MAPTMAPK1CASP3 | |
| SCHEMBL17548192 | 0.81 | SMN1; SMN2 (0.48) | AGBL2DPP4SMN1; SMN2MAPTMAOB | |
| SCHEMBL31042960 | 0.81 | AGBL2 (0.48) | AGBL2DPP4SMN1; SMN2MAPTMAOB | |
| SCHEMBL10515102 | 0.81 | MEN1 (0.40) | DPP4SMN1; SMN2MAPTMAPK1CASP3 | |
| SCHEMBL23566852 | 0.80 | AGBL2 (0.51) | AGBL2AGTR1AGTR2MEN1KMT2A | |
| SCHEMBL10515471 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTMAPK1CASP3CASP7 | |
| SCHEMBL17548191 | 0.80 | AGBL2 (0.43) | AGBL2DPP4SMN1; SMN2MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4674841-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2026-01-07 | — | — | EP | disclosed |
| CN-118973578-A | Pharmaceutical compounds | 杜克街生物有限公司 | 2024-11-15 | — | — | CN | disclosed |
| EP-4444305-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |