SCHEMBL25366166

SCHEMBL25366166

Cc1ccc(C)c2nc3c(cc12)CNCCO3

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SSTR4 P31391 10/20 0.41
▸ SSTR1 P30872 1/20 0.35
▸ SSTR2 P30874 1/20 0.35
▸ SSTR3 P32745 1/20 0.35
▸ SSTR5 P35346 1/20 0.35
▸ ALDH1A1 P00352 3/20 0.34
▸ KDM4E B2RXH2 3/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ TSHR P16473 2/20 0.33
▸ USP2 O75604 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ CASP1 P29466 1/20 0.33
▸ CASP7 P55210 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ MEN1 O00255 1/20 0.31
▸ GLA P06280 1/20 0.31
▸ PKM P14618 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30588955 1.00 SSTR4 (0.41) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL22744576 0.83 SSTR4 (0.41) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL10200081 0.73 CDK7 (0.37) SSTR4APEX1MAP4K1
SCHEMBL22744288 0.72 MEN1 (0.37) SSTR4ALDH1A1KDM4ETSHRMAPT
Hydrochloric Acid SCHEMBL2111829 0.72 CDK7 (0.36) SSTR4APEX1MAP4K1
SCHEMBL22744378 0.70 MAPT (0.38) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL2109252 0.70 S1PR1 (0.35) SSTR4APEX1
SCHEMBL30588965 0.70 MAPT (0.38) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL13970701 0.70 S1PR1 (0.30) —
Hydrochloric Acid SCHEMBL2111977 0.69 S1PR1 (0.34) SSTR4APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230272401-A1 COMPOSITIONS FOR FLCN GENE MODULATION AND METHODS THEREOF Genetic Intelligence, Inc 2023-08-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230272401-A1 COMPOSITIONS FOR FLCN GENE MODULATION AND METHODS THEREOF TARDBP, FUS, RBM17 SSTR4 4870/4885SSTR1 4861/4885SSTR2 4863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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