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RBM17

Splicing factor 45 · Q96I25 · RBM17 on Sugi Atlas →

17 patent compounds predicted against RBM17, 12 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL8828624 SCHEMBL8828624 0.55 1/20
SCHEMBL28513930 SCHEMBL28513930 0.54 1/20
SCHEMBL7489821 SCHEMBL7489821 0.54 1/20
SCHEMBL29379828 SCHEMBL29379828 0.53 1/20
SCHEMBL14979457 SCHEMBL14979457 0.51 1/20
SCHEMBL11771305 SCHEMBL11771305 0.43 1/20
SCHEMBL11771223 SCHEMBL11771223 0.42 1/20
SCHEMBL22747648 SCHEMBL22747648 0.42 1/20
SCHEMBL5810111 SCHEMBL5810111 0.42 1/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL5805233) 0.41 1/20
SCHEMBL11772522 SCHEMBL11772522 0.41 1/20
SCHEMBL22747652 SCHEMBL22747652 0.40 1/20

Clinical trials — most relevant to RBM17 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Biocollection in MyeloDysplastic Syndrome (P-MDS) nanRECRUITING
SRSF2 Gene Mutation in Patients With t-MDS/AML nanCOMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
Mechanisms of Cell Death in Spinal Muscular Atrophy nanCOMPLETED
Molecular Disease Profile of Hematological Malignancies nanUNKNOWN
SMN Circular RNAs as Potential Biomarkers for the Therapeutic Response to Nusinersen in Spinal Muscular Atrophy Patients nanUNKNOWN
Expression Pattern of HNRNPH1 and HNRNPK Genes in MPNs nanUNKNOWN
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Patient's Derived Organoids for Drug Screening in Glioblastoma nanNOT_YET_RECRUITING
Efficacy and Safety Study of EGCG/Tocotrienol in 18 Patients With Splicing-mutation-mediated Cystic Fibrosis (CF) nanCOMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Identification and Characterization of Novel Non-Coding Variants That Contribute to Genetic Disorders nanCOMPLETED
Research for Individualized Therapeutics in Rare Genetic Disease nanENROLLING_BY_INVITATION
Clinical Study of Spinal Muscular Atrophy nanCOMPLETED
Precision Diagnosis and Therapy for Rare Diseases by Interpreting Non-coding Genomes nanRECRUITING
Immunophenotyping and Xist Gene in AML nanUNKNOWN
Transcriptomes Breast, Ovarian and Leukocyte Hereditary Genes Predisposing to Breast and / or Ovarian Cancer nanCOMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
Becker Muscular Dystrophy - A Natural History Study to Predict Efficacy of Exon Skipping nanUNKNOWN
Home Monitoring of Adult Patients With SMA: a Pilot Multicenter Validation Study nanUNKNOWN
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes nanUNKNOWN
Personalized Medicine Program on Myelodysplastic Syndromes: Characterization of the Patient's Genome for Clinical Decision Making and Systematic Collection of Real World Data to Improve Quality of Health Care nanCOMPLETED
Genetic Factors Affecting the Severity of Beta Thalassemia nanCOMPLETED
Developing a Pipeline to Employ RNA-Seq as a Complementary Diagnostic Tool in Rare Diseases nanRECRUITING
Studying Genes in Samples From Younger Patients With Desmoplastic Small Round Cell Tumor Registered on COG-D9902 or COG-ABTR01B1 nanCOMPLETED
RNA Sequencing in the Framingham Heart Study Third Generation Cohort Exam 2 nanCOMPLETED
Outcome Measures and Biomarkers in a Cohort of Spinal Muscular Atrophy Type III/ IV Patients nanACTIVE_NOT_RECRUITING
Pumilio1 (PUM1) Expression, Sickle Cell Anemia, β-thalassemia Intermedia nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a RBM17 binder may also engage these)

ProteinNameSimilarity
Q8JZX4 — 1.000 Q8JZX4 →
P42698 — 1.000 P42698 →
Q94C11 — 0.991 Q94C11 →
U2SURP U2 snRNP-associated SURP motif-containing protein 0.987 landscape →
Q8IWZ8 — 0.986 Q8IWZ8 →
SMARCC2 SWI/SNF complex subunit SMARCC2 0.986 landscape →
Q8RXF1 — 0.985 Q8RXF1 →
P0CR14 — 0.985 P0CR14 →
Q569Z5 — 0.985 Q569Z5 →
Q68FU8 — 0.984 Q68FU8 →
F4ICK8 — 0.984 F4ICK8 →
Q17QX9 — 0.984 Q17QX9 →
Q5R7W3 — 0.984 Q5R7W3 →
RBM26 RNA-binding protein 26 0.984 landscape →
O48713 — 0.983 O48713 →
P53990 — 0.983 P53990 →
CWC27 Spliceosome-associated protein CWC27 homolog 0.983 landscape →
Q7L014 — 0.983 Q7L014 →
Q5U2Y6 — 0.983 Q5U2Y6 →
Q8BTV2 — 0.983 Q8BTV2 →
Q9FNG6 — 0.983 Q9FNG6 →
Q4R4J1 — 0.983 Q4R4J1 →
Q0V898 — 0.983 Q0V898 →
Q62780 — 0.983 Q62780 →
Q5R6D8 — 0.983 Q5R6D8 →
B2RY56 — 0.983 B2RY56 →
P55876 — 0.982 P55876 →
Q90X38 — 0.982 Q90X38 →
Q5XI29 — 0.982 Q5XI29 →
A1XD94 — 0.982 A1XD94 →