SCHEMBL25369016

SCHEMBL25369016

Cn1nc(C(F)(F)F)cc1S(=O)(=O)N1CC2(CN(CC3CCOC3)C2)C1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CTSK P43235 1/20 0.35
▸ TLR7 Q9NYK1 1/20 0.35
▸ EBP Q15125 2/20 0.33
▸ MGLL Q99685 1/20 0.33
▸ PARG Q86W56 7/20 0.33
▸ OPRM1 P35372 1/20 0.32
▸ OPRL1 P41146 1/20 0.32
▸ MLNR O43193 1/20 0.32
▸ PTGS1 P23219 1/20 0.32
▸ PTGS2 P35354 1/20 0.32
▸ CYP11B2 P19099 1/20 0.31
▸ UBE2M P61081 1/20 0.30
▸ DCUN1D1 Q96GG9 1/20 0.30
▸ CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30567055 1.00 CTSK (0.35) CTSKTLR7EBPMGLLPARG
SCHEMBL25373929 1.00 CTSK (0.35) CTSKTLR7EBPMGLLPARG
SCHEMBL25369931 0.94 EBP (0.38) CTSKEBPOPRM1OPRL1PTGS1
SCHEMBL25372158 0.93 CTSK (0.38) CTSKOPRM1OPRL1
SCHEMBL25370615 0.87 EBP (0.37) EBPCNR2
SCHEMBL26066102 0.87 MLNR (0.36) CTSKTLR7EBPPARGMLNR
SCHEMBL25370731 0.86 KCNH2 (0.35) CTSKOPRM1OPRL1
SCHEMBL25371573 0.86 KCNH2 (0.35) CTSKOPRM1OPRL1
SCHEMBL25373285 0.86 KCNH2 (0.35) CTSKOPRM1OPRL1
SCHEMBL25371433 0.85 CTSK (0.37) CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250171463-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. 2025-05-29 — — US disclosed
WO-2023164063-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-08-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171463-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF EBPL, EBP, CREBBP CTSK 4031/4885TLR7 4820/4885EBP 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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