Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 10/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30642005 | 1.00 | PARP1 (0.51) | PARP1PDE10APARP2TNKSMEN1 | |
| SCHEMBL25366837 | 0.83 | CCNB2 (0.43) | PARP1PDE10AMEN1KMT2AMAPT | |
| SCHEMBL30642000 | 0.83 | CCNB2 (0.43) | PARP1PDE10AMEN1KMT2AMAPT | |
| SCHEMBL25368196 | 0.81 | MAPT (0.40) | PDE10AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL30641999 | 0.81 | MAPT (0.40) | PDE10AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL26042892 | 0.78 | TDP1 (0.43) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL31467354 | 0.78 | TDP1 (0.43) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL31467294 | 0.76 | MAPT (0.41) | PDE10AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL26042891 | 0.76 | MAPT (0.41) | PDE10AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL23882091 | 0.74 | KDM4E (0.52) | TNKSMEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023161881-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-08-31 | — | — | WO | disclosed |