Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31467294 | 1.00 | MAPT (0.41) | MAPTTSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL25368196 | 0.94 | MAPT (0.40) | MAPTTSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL30641999 | 0.94 | MAPT (0.40) | MAPTTSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL26042892 | 0.93 | TDP1 (0.43) | MAPTTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL31467354 | 0.93 | TDP1 (0.43) | MAPTTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL26042893 | 0.86 | SMN1; SMN2 (0.37) | MAPTALDH1A1KDM4ECYP1A2HPGD | |
| SCHEMBL31467368 | 0.86 | SMN1; SMN2 (0.37) | MAPTALDH1A1KDM4ECYP1A2HPGD | |
| SCHEMBL30642005 | 0.76 | PARP1 (0.51) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL25370415 | 0.76 | PARP1 (0.51) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL5029517 | 0.73 | MCHR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023161881-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-08-31 | — | — | WO | disclosed |