SCHEMBL25370910

SCHEMBL25370910

Cc1ccc(S(=O)(=O)N2CC3(CN(C(=O)OC(C)(C)C)C3)C2)c(C)c1

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 8/20 0.59
▸ F13A1 P00488 1/20 0.50
▸ TGM2 P21980 1/20 0.50
▸ TGM1 P22735 1/20 0.50
▸ LMNA P02545 4/20 0.46
▸ SMN1; SMN2 Q16637 3/20 0.45
▸ GAA P10253 1/20 0.45
▸ TSHR P16473 1/20 0.45
▸ ATM Q13315 1/20 0.45
▸ HTT P42858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25371482 0.91 EPHX2 (0.60) EPHX2F13A1TGM2TGM1LMNA
SCHEMBL896572 0.84 TGM2 (0.48) F13A1TGM2TGM1
SCHEMBL26065003 0.82 EPHX2 (0.53) EPHX2
SCHEMBL30567086 0.82 EPHX2 (0.53) EPHX2
SCHEMBL30490261 0.78 F13A1 (0.50) EPHX2F13A1TGM2TGM1
SCHEMBL31467619 0.78 TGM2 (0.41) EPHX2F13A1TGM2TGM1
SCHEMBL25371565 0.78 F13A1 (0.39) EPHX2F13A1TGM2TGM1
SCHEMBL23850527 0.77 EPHX2 (0.48) EPHX2F13A1TGM2TGM1
SCHEMBL29497041 0.77 EPHX2 (0.48) EPHX2F13A1TGM2TGM1
SCHEMBL30490344 0.77 F13A1 (0.48) F13A1TGM2TGM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250171463-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. 2025-05-29 — — US disclosed
EP-4482587-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-01-01 — — EP disclosed
WO-2023164063-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-08-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171463-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF EBPL, EBP, CREBBP EPHX2 2219/4885F13A1 1940/4885TGM2 1281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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