SCHEMBL25373726

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25662634	0.88	EGFR (0.49)	EGFRMAPTMAPK1AHRHTT
	SCHEMBL25249103	0.86	EGFR (0.45)	EGFRMAPTHTTCYP1A2
	SCHEMBL26058048	0.84	EGFR (0.43)	EGFRMAPTMAPK1AHRHTT
	SCHEMBL25373220	0.83	EGFR (0.47)	EGFRAHRMAP4K4METKDR
	SCHEMBL25216766	0.82	EGFR (0.56)	EGFRLRRK2ERBB2ERBB4CIT
	SCHEMBL29382670	0.82	EGFR (0.46)	EGFRLRRK2ERBB2ERBB4CIT
	SCHEMBL25211108	0.82	EGFR (0.46)	EGFRLRRK2ERBB2ERBB4CIT
	SCHEMBL29383085	0.78	EGFR (0.60)	EGFRAHRERBB2METKDR
	SCHEMBL8870722	0.78	EGFR (0.57)	EGFRMAPK1HTTTTBK1TTBK2
	SCHEMBL25213722	0.77	EGFR (0.51)	EGFRLRRK2ERBB2ERBB4CIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.