Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.60 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.54 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25373220 | 0.88 | EGFR (0.47) | EGFRMETKDRAHRTGFBR1 | |
| SCHEMBL25250811 | 0.79 | EGFR (0.48) | EGFRTGFBR1 | |
| SCHEMBL25663470 | 0.79 | TGFBR1 (0.46) | EGFRMETKDRTGFBR1 | |
| SCHEMBL25373726 | 0.78 | EGFR (0.48) | EGFRERBB2METKDRAHR | |
| SCHEMBL25662619 | 0.76 | EGFR (0.56) | EGFRERBB2KDR | |
| SCHEMBL29690398 | 0.76 | EGFR (1.00) | EGFRERBB2AHR | |
| SCHEMBL30513 | 0.76 | EGFR (1.00) | EGFRERBB2AHR | |
| Hydrochloric Acid SCHEMBL7760887 | 0.75 | EGFR (0.76) | EGFRERBB2AHR | |
| SCHEMBL25371562 | 0.75 | TGFBR1 (0.43) | EGFRERBB2METKDRTGFBR1 | |
| SCHEMBL25258592 | 0.75 | EGFR (0.53) | EGFRERBB2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022033410-A1 | EFGR INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海和誉生物医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |