Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | F7 | P08709 | 1/20 | 0.61 |
| ▸ | F3 | P13726 | 1/20 | 0.61 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.61 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.61 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.61 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.61 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.61 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL123932 | 0.83 | ALDH1A1 (0.47) | POLBALDH1A1GAAMAPTCYP3A4 | |
| SCHEMBL123933 | 0.83 | ALDH1A1 (0.47) | POLBALDH1A1GAAMAPTCYP3A4 | |
| SCHEMBL123931 | 0.83 | ALDH1A1 (0.47) | POLBALDH1A1GAAMAPTCYP3A4 | |
| Niacinamide SCHEMBL4601203 | 0.79 | F7 (0.88) | POLBF7F3SARM1SIRT2 | |
| SCHEMBL28507362 | 0.79 | POLB (0.52) | POLBF7F3SARM1SIRT2 | |
| Niacinamide SCHEMBL4730414 | 0.79 | F7 (0.96) | POLBF7F3SARM1SIRT2 | |
| Niacinamide SCHEMBL675207 | 0.79 | F7 (0.96) | POLBF7F3SARM1SIRT2 | |
| Niacinamide SCHEMBL11483547 | 0.77 | F7 (0.92) | POLBF7F3SARM1SIRT2 | |
| Niacinamide SCHEMBL28157721 | 0.77 | F7 (0.92) | POLBF7F3SARM1SIRT2 | |
| SCHEMBL2928423 | 0.77 | POLB (0.62) | POLBF7F3SARM1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109867623-B | 3-pyridyl-3-amino-2-cyanoacrylate compounds and preparation method and application thereof | 江苏省农药研究所股份有限公司 | 2021-02-09 | — | — | CN | claimed |
| CN-119431188-A | 2-Cyano-3-disubstituted phenyl acrylate compound, preparation method thereof and application thereof in pesticides | 江苏省中国科学院植物研究所 | 2025-02-14 | — | — | CN | disclosed |
| US-20240298639-A1 | 2-CYANOACRYLATE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | ZHEJIANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2024-09-12 | — | — | US | disclosed |
| EP-4238958-A1 | 2-CYANOACRYLATE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Zhejiang University (CN) | 2023-09-06 | — | — | EP | disclosed |
| CN-109867623-B | 3-pyridyl-3-amino-2-cyanoacrylate compounds and preparation method and application thereof | 江苏省农药研究所股份有限公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-109867623-B | 3-pyridyl-3-amino-2-cyanoacrylate compounds and preparation method and application thereof | 江苏省农药研究所股份有限公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-109867623-B | 3-pyridyl-3-amino-2-cyanoacrylate compounds and preparation method and application thereof | 江苏省农药研究所股份有限公司 | 2021-02-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240298639-A1 | 2-CYANOACRYLATE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CYP51A1, FAR1, CYP4F11 | POLB 4386/4885F7 594/4885F3 1379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.